Evidence map›Paper›PMID 29614386›Full record

ArticleEnvironmental research2018

Residential agricultural pesticide exposures and risks of preeclampsia.

Gary M Shaw, Wei Yang, Eric M Roberts, Nima Aghaeepour, Jonathan A Mayo, Kari A Weber, Ivana Maric, Suzan L Carmichael, Virginia D Winn, David K Stevenson and 1 more

Abstract read
In one paragraph

Article in Environmental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Environmental contaminants and preeclampsia: a systematic literature review.Journal of toxicology and environmental health. Part B, Critical reviews · 2018
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Residential proximity to green space and preeclampsia in California.Environmental epidemiology (Philadelphia, Pa.) · 2020
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gary M ShawMarch of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: gmshaw@stanford.edu.
Wei YangMarch of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Eric M RobertsPublic Health Institute, Oakland, CA 94607, USA.
Nima AghaeepourStanford University, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford, CA 94305, USA.
Jonathan A MayoMarch of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Kari A WeberMarch of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Ivana MaricMarch of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Suzan L CarmichaelMarch of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Virginia D WinnStanford University, Department of Obstetrics and Gynecology, Stanford, CA 94305, USA.
David K StevensonMarch of Dimes Prematurity Research Center at Stanford University, Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Paul B EnglishCalifornia Department of Public Health, Richmond, CA 94804, USA.

Funding

Pesticide Exposures and Risk of Preterm BirthR01HD075761 · NICHD · STANFORD UNIVERSITY · PI SHAW, GARY M · 2013 to 2016
$1.2M
NICHD NIH HHS R01 HD075761
6 · The paper itself

Abstract

We investigated risks of preeclampsia phenotypes from potential residential pesticide exposures, including 543 individual chemicals and 69 physicochemical groupings that were applied in the San Joaquin Valley of California during the study period, 1998-2011. The study population was derived from birth certificate data linked with Office of Statewide Health Planning and Development maternal and infant hospital discharge data. The following numbers of women with preeclampsia phenotypes were identified: 1045 with superimposed (pre-existing hypertension with preeclampsia) preeclampsia (265 with gestational weeks 20-31 and 780 with gestational weeks 32-36); 3471 with severe preeclampsia (824 with gestational weeks 20-31 and 2647 with gestational weeks 32-36); and 2780 with mild preeclampsia (207 with gestational weeks 20-31 and 2573 with gestational weeks 32-36). The reference population for these groups was 197,461 women who did not have diabetes (gestational or pre-existing), did not have any hypertensive disorder, and who delivered at 37 weeks or later. The frequency of any exposure was lower or about the same in each preeclampsia case group (further delineated by gestational age), and month time period, relative to the frequency in reference population controls. Nearly all odds ratios were below 1.0 for these any vs no exposure comparisons. This study showed a general lack of increased risks between a range of agriculture pesticide exposures near women's residences and various preeclampsia phenotypes.

Indexed as

PesticidesPre-EclampsiaAgricultureCaliforniaEnvironmental ExposureFemaleHumansMaternal ExposurePregnancyPesticidesEndocrine disruptorsEnvironmentHypertensionPesticidesPregnancy

Identifiers

PMID29614386
PMCPMC5911197

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.