Evidence map›Paper›PMID 29614238›Full record

ArticleAmerican journal of respiratory and critical care medicine2018

Changes in Lung Clearance Index in Preschool-aged Patients with Cystic Fibrosis Treated with Ivacaftor (GOAL): A Clinical Trial.

Felix Ratjen, Michelle Klingel, Philip Black, Michael R Powers, Hartmut Grasemann, Melinda Solomon, Scott D Sagel, Scott H Donaldson, Steven M Rowe, Margaret Rosenfeld

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Ivacaftor in Omani children with cystic fibrosis caused by p.Ser549Arg CFTR mutation.International journal of pediatrics & adolescent medicine · 2022
    Article
  9. Observational
  10. Article
  11. Review
  12. Article
  13. New Therapies to Correct the Cystic Fibrosis Basic Defect.International journal of molecular sciences · 2021
    Review
  14. Review
  15. Article
  16. Update in Cystic Fibrosis 2018.American journal of respiratory and critical care medicine · 2019
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Felix Ratjen1 University of Toronto Toronto, Ontario, Canada.
Michelle Klingel1 University of Toronto Toronto, Ontario, Canada.
Philip Black2 Children's Mercy Hospital Kansas City, Missouri.
Michael R Powers3 Oregon Health & Sciences University Portland, Oregon.
Hartmut Grasemann1 University of Toronto Toronto, Ontario, Canada.
Melinda Solomon1 University of Toronto Toronto, Ontario, Canada.
Scott D Sagel4 University of Colorado School of Medicine Aurora, Colorado.
Scott H Donaldson5 North Carolina Children's Hospital Chapel Hill, North Carolina.
Steven M Rowe6 University of Alabama at Birmingham Birmingham, Alabama and.
Margaret Rosenfeld7 Seattle's Children's Hospital Seattle, Washington.

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Susan Elizabeth Birket · 2007 to 2026
$23.0M
Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
NCATS NIH HHS UL1 TR002369NIDDK NIH HHS P30 DK072482NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminophenolsChild, PreschoolChloride Channel AgonistsCystic FibrosisFemaleHumansLungMaleQuinolonesTreatment OutcomeAminophenolsChloride Channel AgonistsivacaftorQuinolones

Identifiers

PMID29614238
PMCPMC6835087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.