Evidence map›Paper›PMID 29614055›Full record

ArticleInternational journal of molecular sciences2018

Cell-Specific PEAR1 Methylation Studies Reveal a Locus that Coordinates Expression of Multiple Genes.

Benedetta Izzi, Fabrizia Noro, Katrien Cludts, Kathleen Freson, Marc F Hoylaerts

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Epigenetics · 2021
    Article
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Benedetta IzziDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium. izzi.epigenomica@gmail.com.
Fabrizia NoroDepartment of Epidemiology and Prevention, IRCCS Istituto Neurologico Mediterraneo Neuromed, Via dell'Elettronica, 86077 Pozzilli (IS), Italy. fabrizia.noro@moli-sani.org.
Katrien CludtsDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium. Katrien.cludts@uzleuven.be.
Kathleen FresonDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium. Kathleen.freson@Kuleuven.be.ORCID 0000-0002-4381-2442
Marc F HoylaertsDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium. Marc.hoylaerts@kuleuven.be.
KU Leuven · BEIstituto Neurologico Mediterraneo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosomal interactions connect distant enhancers and promoters on the same chromosome, activating or repressing gene expression.

Indexed as

DNA MethylationCell Cycle ProteinsCpG IslandsExodeoxyribonucleasesHeparin-binding EGF-like Growth FactorHumansHuman Umbilical Vein Endothelial CellsNeoplasm ProteinsPromoter Regions, GeneticReceptors, Cell SurfaceAEN protein, humanCell Cycle ProteinsExodeoxyribonucleasesHeparin-binding EGF-like Growth FactorNeoplasm ProteinsPEAR1 protein, humanPRCC protein, humanReceptors, Cell Surfacechromosome interactionsDNA methylationPEAR1

Identifiers

PMID29614055
PMCPMC5979289
OpenAlexW2796455464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.