Evidence map›Paper›PMID 29613851›Full record

ArticleJournal of medical Internet research2018

Solution to Detect, Classify, and Report Illicit Online Marketing and Sales of Controlled Substances via Twitter: Using Machine Learning and Web Forensics to Combat Digital Opioid Access.

Tim Mackey, Janani Kalyanam, Josh Klugman, Ella Kuzmenko, Rashmi Gupta

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  7. Illicit Online Pharmacies: A Scoping Review.International journal of environmental research and public health · 2023
    Article
  8. Adaptive interventions for opioid prescription management and consumption monitoring.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  9. Article
  10. Review
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  18. Developing a framework regarding a complex risk based methodology in the evaluation of hazards associated with medicinal products sourced via the internet.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tim Mackey *Division of Infectious Disease and Global Public Health, Department of Anesthesiology, School of Medicine, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0002-2191-7833
Janani Kalyanam *Department of Electrical and Computer Engineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, United States.ORCID 0000-0001-9795-4844
Josh KlugmanIBM Global Business Services, Washington, DC, United States.ORCID 0000-0002-8941-4124
Ella KuzmenkoIBM Global Business Services, Washington, DC, United States.ORCID 0000-0003-0761-1800
Rashmi GuptaCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID 0000-0002-0363-3343

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOn December 6 and 7, 2017, the US Department of Health and Human Services (HHS) hosted its first Code-a-Thon event aimed at leveraging technology and data-driven solutions to help combat the opioid epidemic. The authors—an interdisciplinary team from academia, the private sector, and the US Centers for Disease Control and Prevention—participated in the Code-a-Thon as part of the prevention track.

objectiveThe aim of this study was to develop and deploy a methodology using machine learning to accurately detect the marketing and sale of opioids by illicit online sellers via Twitter as part of participation at the HHS Opioid Code-a-Thon event.

methodsTweets were collected from the Twitter public application programming interface stream filtered for common prescription opioid keywords in conjunction with participation in the Code-a-Thon from November 15, 2017 to December 5, 2017. An unsupervised machine learning–based approach was developed and used during the Code-a-Thon competition (24 hours) to obtain a summary of the content of the tweets to isolate those clusters associated with illegal online marketing and sale using a biterm topic model (BTM). After isolating relevant tweets, hyperlinks associated with these tweets were reviewed to assess the characteristics of illegal online sellers.

resultsWe collected and analyzed 213,041 tweets over the course of the Code-a-Thon containing keywords codeine, percocet, vicodin, oxycontin, oxycodone, fentanyl, and hydrocodone. Using BTM, 0.32% (692/213,041) tweets were identified as being associated with illegal online marketing and sale of prescription opioids. After removing duplicates and dead links, we identified 34 unique “live” tweets, with 44% (15/34) directing consumers to illicit online pharmacies, 32% (11/34) linked to individual drug sellers, and 21% (7/34) used by marketing affiliates. In addition to offering the “no prescription” sale of opioids, many of these vendors also sold other controlled substances and illicit drugs.

conclusionsThe results of this study are in line with prior studies that have identified social media platforms, including Twitter, as a potential conduit for supply and sale of illicit opioids. To translate these results into action, authors also developed a prototype wireframe for the purposes of detecting, classifying, and reporting illicit online pharmacy tweets selling controlled substances illegally to the US Food and Drug Administration and the US Drug Enforcement Agency. Further development of solutions based on these methods has the potential to proactively alert regulators and law enforcement agencies of illegal opioid sales, while also making the online environment safer for the public.

Indexed as

Analgesics, OpioidControlled SubstancesHumansInternetMachine LearningMarketingPharmaceutical Services, OnlinePrescription Drug MisuseSocial MediaAnalgesics, OpioidControlled Substancesdrug abusemachine learningonline pharmaciesopioid abuseprescription drug misuseunsupervised machine learning

Identifiers

PMID29613851
PMCPMC5948414

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.