Evidence map›Paper›PMID 29611451›Full record

Trial reportJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2018

Permeability imaging as a predictor of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.

Jonathan J Russin, Axel Montagne, Francesco D'Amore, Shuhan He, Mark S Shiroishi, Robert C Rennert, Jena Depetris, Berislav V Zlokovic, William J Mack

Open access · bronzeAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Elevated Cerebrospinal Fluid Protein Is Associated with Unfavorable Functional Outcome in Spontaneous Subarachnoid Hemorrhage.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020
    Observational
  11. Review
  12. Review
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Brain endothelial cell junctions after cerebral hemorrhage: Changes, mechanisms and therapeutic targets.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jonathan J Russin1 USC Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Axel Montagne2 Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Francesco D'Amore3 Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Shuhan He2 Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Mark S Shiroishi3 Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Robert C Rennert1 USC Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Jena Depetris2 Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-2544-7496
Berislav V Zlokovic2 Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
William J Mack2 Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
University of Southern California · US

Funding

Vascular Contributions to Dementia and Genetic Risk Factors for Alzheimer's DiseaseP01AG052350 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Daniel A Nation, ARTHUR W TOGA · 2016 to 2026
$28.4M
Neurotoxicity of Airborne Particles: Role of Chronic Cerebral HypoperfusionR01ES024936 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MACK, WILLIAM J · 2015 to 2019
$2.4M
NIA NIH HHS P01 AG052350NIEHS NIH HHS R01 ES024936
6 · The paper itself

Abstract

Blood-brain barrier (BBB) dysfunction has been implicated in ischemic risk following aneurysmal subarachnoid hemorrhage (aSAH), but never directly imaged. We prospectively examined whether post-bleed day 4 dynamic contrast-enhanced magnetic resonance (DCE-MR) BBB permeability imaging could predict development of delayed cerebral ischemia (DCI). Global MR-derived BBB permeability ( K

Indexed as

Magnetic Resonance ImagingAdultAgedAged, 80 and overBlood-Brain BarrierBrain IschemiaFemaleHumansMaleMiddle AgedPermeabilityPredictive Value of TestsSubarachnoid HemorrhageVasospasm, Intracranialaneurysmblood–brain barrierDelayed cerebral ischemiadynamic contrast-enhanced magnetic resonance imagingsubarachnoid hemorrhage

Identifiers

PMID29611451
PMCPMC5998996
OpenAlexW2795650841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.