Evidence map›Paper›PMID 29611126›Full record

ReviewEnvironmental science and pollution research international2018

Mode of action of nanoparticles against insects.

Giovanni Benelli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
40.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 353 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Insects · 2026
    Article
  10. Bioinspired Ag/CeOScientific reports · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Evaluation of silver nanoparticles for controllingFrontiers in insect science · 2026
    Article
  17. Review
  18. Article
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Giovanni BenelliDepartment of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124, Pisa, Italy. benelli.giovanni@gmail.com.ORCID http://orcid.org/0000-0001-8971-6010
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The employment of nanoparticles obtained through various synthesis routes as novel pesticides recently attracted high research attention. An impressive number of studies have been conducted to test their toxic potential against a wide number of arthropod pests and vectors, with major emphasis on mosquitoes and ticks. However, precise information on the mechanisms of action of nanoparticles against insects and mites are limited, with the noteworthy exception of silica, alumina, silver, and graphene oxide nanoparticles on insects, while no information is available for mites. Here, I summarize current knowledge about the mechanisms of action of nanoparticles against insects. Both silver and graphene oxide nanoparticles have a significant impact on insect antioxidant and detoxifying enzymes, leading to oxidative stress and cell death. Ag nanoparticles also reduced acetylcholinesterase activity, while polystyrene nanoparticles inhibited CYP450 isoenzymes. Au nanoparticles can act as trypsin inhibitors and disrupt development and reproduction. Metal nanoparticles can bind to S and P in proteins and nucleic acids, respectively, leading to a decrease in membrane permeability, therefore to organelle and enzyme denaturation, followed by cell death. Besides, Ag nanoparticles up- and downregulate key insect genes, reducing protein synthesis and gonadotrophin release, leading to developmental damages and reproductive failure. The toxicity of SiO

Indexed as

AcaricidesInsectaInsecticidesMitesNanoparticlesAnimalsMetal NanoparticlesAcaricidesInsecticidesAcetylcholinesteraseAcute toxicityAlumina nanoparticlesAquatic toxicologyCYP450 isoenzymesDengueInsecticideIntegrated vector managementInvertebrate toxicologyLyme diseaseMalariaMechanism of actionMitesMosquito controlMosquito vectorsPolystyrene nanoparticlesSilica nanoparticlesSilver nanoparticlesTicksTitania nanoparticlesTrypsin inhibitorZika virusZinc oxide nanoparticles

Identifiers

PMID29611126
OpenAlexW2796418023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.