Evidence map›Paper›PMID 29611093›Full record

ArticlePsychometrika2018

Nonlinear Predictive Models for Multiple Mediation Analysis: With an Application to Explore Ethnic Disparities in Anxiety and Depression Among Cancer Survivors.

Qingzhao Yu, Kaelen L Medeiros, Xiaocheng Wu, Roxanne E Jensen

Abstract read
In one paragraph

Article in Psychometrika, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Calidad de Vida: a systematic review of quality of life in Latino cancer survivors in the USA.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qingzhao YuBiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center, 3rd Floor, 2020 Gravier Street, New Orleans, LA, 70112, USA. qyu@lsuhsc.edu.ORCID 0000-0001-8194-0798
Kaelen L MedeirosAmerican College of Surgeon, Chicago, IL, USA.
Xiaocheng WuLouisiana Tumor Registry, 2020 Gravier Street, New Orleans, LA, 70112, USA.
Roxanne E JensenCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Washington, DC, USA.

Funding

Trends of disparities in breast cancer progression and health care considering multilevel risk factorsR15MD012387 · NIMHD · LSU HEALTH SCIENCES CENTER · PI YU, QINGZHAO · 2017 to 2023
$1.1M
NIMHD NIH HHS 1R15MD012387NIMHD NIH HHS R15 MD012387
6 · The paper itself

Abstract

Mediation analysis allows the examination of effects of a third variable (mediator/confounder) in the causal pathway between an exposure and an outcome. The general multiple mediation analysis method (MMA), proposed by Yu et al., improves traditional methods (e.g., estimation of natural and controlled direct effects) to enable consideration of multiple mediators/confounders simultaneously and the use of linear and nonlinear predictive models for estimating mediation/confounding effects. Previous studies find that compared with non-Hispanic cancer survivors, Hispanic survivors are more likely to endure anxiety and depression after cancer diagnoses. In this paper, we applied MMA on MY-Health study to identify mediators/confounders and quantify the indirect effect of each identified mediator/confounder in explaining ethnic disparities in anxiety and depression among cancer survivors who enrolled in the study. We considered a number of socio-demographic variables, tumor characteristics, and treatment factors as potential mediators/confounders and found that most of the ethnic differences in anxiety or depression between Hispanic and non-Hispanic white cancer survivors were explained by younger diagnosis age, lower education level, lower proportions of employment, less likely of being born in the USA, less insurance, and less social support among Hispanic patients.

Indexed as

Data Interpretation, StatisticalModels, StatisticalAdultAgedAged, 80 and overAnxietyCancer SurvivorsDepressionFemaleFollow-Up StudiesHispanic or LatinoHumansMaleMiddle AgedNonlinear DynamicsPsychometricsethnic disparityhealth-related quality of lifemediation/confounding analysisMY-Health studynonlinear models

Identifiers

PMID29611093
PMCPMC6168435

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.