ArticleJapanese journal of radiology2018
Analysis of computed tomography density of liver before and after amiodarone administration.
Article in Japanese journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Key CT and MRI findings of drug-associated hepatobiliary and pancreatic disorders.Japanese journal of radiology · 2024Review
- Amiodarone-induced hepatotoxicity.BMJ case reports · 2023Article
- Other types of diffuse liver disease: is there a way to do it?Abdominal radiology (New York) · 2020Review
- Iodine accumulation of the liver in patients treated with amiodarone can be unmasked using material decomposition from multiphase spectral-detector CT.Scientific reports · 2020Article
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Authors and funding
6 authors.
Funding
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Abstract
purposeTo evaluate CT density of liver changes between before and after amiodarone administration. MATERIALS AND
methodsTwenty-five patients underwent non-enhanced CT including the liver before and after amiodarone administration. We set regions of interest (ROIs) at liver S8, spleen, paraspinal muscle, and calculated average CT density in these ROIs, then compared CT density between liver and other organs. Statistical differences between CT density of liver and various ratios before and after administration were determined, along with correlations between cumulative dose of amiodarone and liver density after administration, density change of liver, and various ratios after administration.
resultsLiver density, liver-to-spleen ratio, and liver-to-paraspinal muscle ratio differed significantly between before and after amiodarone administration. No significant correlations were found between cumulative doses of amiodarone and any of liver density after administration, density change of liver, or various ratios after administration.
conclusionCT density of liver after amiodarone administration was significantly higher than that before administration. No correlations were identified between cumulative dose of amiodarone and either liver density after administration or density change of liver. Amiodarone usage should be checked when radiologists identify high density of the liver on CT.
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