Evidence map›Paper›PMID 29610930›Full record

ArticleWorld journal of surgery2018

Analysis of Early and Long-Term Oncologic Outcomes After Converted Laparoscopic Resection Compared to Primary Open Surgery for Rectal Cancer.

Marco Ettore Allaix, Edgar Furnée, Laura Esposito, Massimiliano Mistrangelo, Fabrizio Rebecchi, Alberto Arezzo, Mario Morino

2 registry-linked trialsOpen access · greenAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04401787 nacompletednot on this map

Is There Better Oncological and Short Term Outcome for Laparoscopic Resection of Upper Rectal Carcinoma T1-4 N0-1 Over Laparoscopic Converted Cases in Obese Patients?

TypeinterventionalSponsorZagazig UniversityRan2016 to 2020Enrolled156ConditionsCancer, RectumArmsAnterior resection for upper rectal cancer in obese
NCT04589975 completednot on this map

Conversion to open surgery in laparoscopic colorectal cancer resection: predictive factors and its impact on long-term outcomes. a retrospective cohort study

TypeobservationalSponsorClinica Universidad de Navarra, Universidad de NavarraRan2000 to 2018Enrolled829ConditionsSurgery, Colorectal Neoplasm, LaparoscopyArmslaparoscopic surgery
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marco Ettore AllaixDepartment of Surgical Sciences, University of Torino, Corso Dogliotti 14, 10126, Turin, Italy. meallaix@gmail.com.
Edgar FurnéeDepartment of Surgical Sciences, University of Torino, Corso Dogliotti 14, 10126, Turin, Italy.
Laura EspositoDepartment of Surgical Sciences, University of Torino, Corso Dogliotti 14, 10126, Turin, Italy.
Massimiliano MistrangeloDepartment of Surgical Sciences, University of Torino, Corso Dogliotti 14, 10126, Turin, Italy.
Fabrizio RebecchiDepartment of Surgical Sciences, University of Torino, Corso Dogliotti 14, 10126, Turin, Italy.
Alberto ArezzoDepartment of Surgical Sciences, University of Torino, Corso Dogliotti 14, 10126, Turin, Italy.
Mario MorinoDepartment of Surgical Sciences, University of Torino, Corso Dogliotti 14, 10126, Turin, Italy.
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic rectal resection (LRR) for cancer is a challenging procedure, with conversion to open surgery being reported in up to 30% of cases. Since only a few studies with short follow-up have compared converted LRR and open RR (ORR), it is unclear if conversion to open surgery should be prevented by preferring an open approach in those patients with preoperatively known risk factors for conversion. The aim of this study was to compare early postoperative outcomes and long-term survival after completed LRR, converted LRR or ORR for non-metastatic rectal cancer.

methodsA prospective database of consecutive curative LRRs and ORRs for rectal cancer was reviewed. Patients undergoing LRR who required conversion (CONV group) were compared with those who had primary open rectal surgery (OPEN group) and completed LRR (LAP group). A multivariate analysis was performed to identify predictors of poor survival.

resultsA total of 537 patients were included in the study: 272 in the LAP group, 49 in the CONV group and 216 in the OPEN group. There were no significant differences in perioperative morbidity, mortality and length of hospital stay between the three groups. Five-year overall survival and disease-free survival rates did not significantly differ between LAP, CONV and OPEN patients: 83.9 versus 77.8 versus 81% (P = 0.398) and 74.5 versus 62.9 versus 72.7% (P = 0.145), respectively. Similar 5-year OS and DFS rates were observed between patients who had converted LRR for locally advanced tumor or for non-tumor-related reasons: 81.2 versus 80.8% (P = 0.839) and 62.5 versus 63.7% (P = 0.970), respectively. Poor grade of tumor differentiation, lymphovascular invasion and a lymph node ratio of 0.25 or greater, but not conversion, were independently associated with poorer survival.

conclusionConversion to open surgery does not impair short-term outcomes and does not jeopardize 5-year survival in patients with rectal cancer when compared to primary open surgery.

Indexed as

Conversion to Open SurgeryLaparoscopyAdultAgedAged, 80 and overDatabases, FactualFemaleFollow-Up StudiesHumansMaleMiddle AgedRectal NeoplasmsRectumRetrospective StudiesSurvival AnalysisTreatment Outcome

Identifiers

PMID29610930
OpenAlexW2796251928

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.