ArticleEvoDevo2018
Characterization of the bHLH family of transcriptional regulators in the acoel
Article in EvoDevo, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- The Acoel nervous system: morphology and development.Neural development · 2024Review
- HES and Mox genes are expressed during early mesoderm formation in a mollusk with putative ancestral features.Scientific reports · 2021Article
- Embryonic development in the acoel Hofstenia miamia.Development (Cambridge, England) · 2021Article
- Acoel Single-Cell Transcriptomics: Cell Type Analysis of a Deep Branching Bilaterian.Molecular biology and evolution · 2021Article
- Neural architecture and regeneration in the acoelProceedings. Biological sciences · 2020Article
- Investigating cellular and molecular mechanisms of neurogenesis in Capitella teleta sheds light on the ancestor of Annelida.BMC evolutionary biology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe basic helix-loop-helix (bHLH) family of transcription factors is one of the largest superfamilies of regulatory transcription factors and is widely used in eukaryotic organisms. They play an essential role in a range of metabolic, physiological, and developmental processes, including the development of the nervous system (NS). These transcription factors have been studied in many metazoans, especially in vertebrates but also in early branching metazoan clades such as the cnidarians and sponges. However, currently very little is known about their expression in the most basally branching bilaterian group, the xenacoelomorphs. Recently, our laboratory has characterized the full complement of bHLH in the genome of two members of the Xenacoelomorpha, the xenoturbellid
resultsHere, we analyze the developmental expression of the whole complement of bHLH genes identified in the acoel
conclusionOur results suggest that the main roles of the bHLH genes of
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Registered trials
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