Evidence map›Paper›PMID 29610629›Full record

ArticleCanadian respiratory journal2018

Digital Clubbing Is Associated with Higher Serum KL-6 Levels and Lower Pulmonary Function in Patients with Interstitial Lung Disease.

Kazushige Shiraishi, Torahiko Jinta, Naoki Nishimura, Hiroshi Nakaoka, Ryosuke Tsugitomi, Kohei Okafuji, Atsushi Kitamura, Yutaka Tomishima, Gautam A Deshpande, Tomohide Tamura

Open access · goldAbstract read
In one paragraph

Article in Canadian respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kazushige ShiraishiDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.ORCID 0000-0001-6510-7157
Torahiko JintaDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.
Naoki NishimuraDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.ORCID 0000-0003-4727-9048
Hiroshi NakaokaDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.
Ryosuke TsugitomiDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.
Kohei OkafujiDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.
Atsushi KitamuraDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.
Yutaka TomishimaDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.
Gautam A DeshpandeCenter for Clinical Epidemiology, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.ORCID 0000-0002-0293-8911
Tomohide TamuraDepartment of Pulmonary Medicine, St. Luke's International University, St. Luke's International Hospital, Tokyo, Japan.
St. Luke's International Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although digital clubbing is a common presentation in patients with interstitial lung disease (ILD), little has been reported regarding its role in assessing patients with ILD. This study evaluated patients with ILD for the presence of clubbing and investigated its association with clinical data. Methods: We evaluated patients with ILD who visited the teaching hospital at which the study was conducted, between October 2014 and January 2015. Clubbing, evaluated using a Vernier caliper for individual patients, was defined as a phalangeal depth ratio > 1. We examined the association of clubbing with clinical data. Results: Of 102 patients with ILD, we identified 17 (16.7%) with clubbing. The partial pressure of oxygen in arterial blood was lower (65.2 ± 5.9 mmHg versus 80.2 ± 3.1 mmHg; Conclusions: Patients with clubbing had lower oxygen levels, higher serum KL-6 levels, and lower pulmonary function than those without clubbing.

Indexed as

AgedAged, 80 and overCross-Sectional StudiesFemaleFingersHumansLung Diseases, InterstitialMaleMiddle AgedMucin-1Respiratory Function TestsRetrospective StudiesMUC1 protein, humanMucin-1

Identifiers

PMID29610629
PMCPMC5828477
OpenAlexW2785920467

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.