Evidence map›Paper›PMID 29610586›Full record

ArticleMaedica2017

Analysis of Interleukin-17 mRNA Level in the Urinary Cells of Kidney Transplant Recipients with Stable Function.

Morteza Bagheri, Ali Taghizadeh-Afshari, Saeed Abkhiz, Isa Abdi-Rad, Mohammadreza Mohammadi-Fallah, Mansour Alizadeh, Saeed Sadeghzadeh

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Maedica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Morteza BagheriNephrology and Kidney Transplant Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Ali Taghizadeh-AfshariNephrology and Kidney Transplant Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Saeed AbkhizNephrology and Kidney Transplant Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Isa Abdi-RadCellular and Molecular Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Mohammadreza Mohammadi-FallahCellular and Molecular Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Mansour AlizadehCellular and Molecular Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Saeed SadeghzadehNephrology and Kidney Transplant Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Urmia University · IRUrmia University of Medical Sciences

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesKidney transplantation supports patients with end-stage kidney diseases. Many factors control the allograft function in kidney transplant recipients. Interleukin-17 (IL-17) can be used as a non-invasive diagnostic biomarker of rejection. The aim of this study was to evaluate the expression of IL-17 mRNA in urinary cells of kidney transplant recipients with stable function. MATERIAL AND

methodsA total of 40 renal transplant recipients who were admitted for surgery and 30 healthy controls were enrolled in the study. From each patient, 30 mL urine samples were collected in 50 mL tubes on days 3 and 5 after renal transplantation; also, 30 mL urine samples were obtained from controls. Quantitative Real-Time PCR (qRT-PCR) technique was used for analysis of IL-17 mRNA level in the tested groups; 2-ÄÄCT method was performed for determining the relative gene expression between tested groups.

resultsThe mRNA expression mean ± SE of fold in patients and controls were 3.58±1.61 fold and 2.85±1.37 fold, respectively. The mRNA expression mean of IL-17 (fold) was not statistically different in tested groups (P-value = 0.63).

conclusionsIn kidney transplant recipients, urinary IL-17 expression provides informative data in relation to the allograft function regardless of allograft pathology.

Identifiers

PMID29610586
PMCPMC5879584
OpenAlexW3024531968

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.