Evidence map›Paper›PMID 29610355›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

The computational form of craving is a selective multiplication of economic value.

Anna B Konova, Kenway Louie, Paul W Glimcher

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Human laboratory models of reward in substance use disorder.Pharmacology, biochemistry, and behavior · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. A neuroeconomic signature of opioid craving: How fluctuations in craving bias drug-related and nondrug-related value.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  11. Article
  12. Computational models of drug use and addiction: A review.Journal of abnormal psychology · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anna B KonovaCenter for Neural Science, New York University, New York, NY 10003; abk288@nyu.edu.ORCID 0000-0001-8894-6164
Kenway LouieCenter for Neural Science, New York University, New York, NY 10003.ORCID 0000-0002-9665-5436
Paul W GlimcherCenter for Neural Science, New York University, New York, NY 10003.

Funding

Vision Core Grant- Design and Fabrication ModuleP30EY013079 · NEI · NEW YORK UNIVERSITY · PI SCHUMAN, JOEL S · 2000 to 2025
$14.2M
Training Systems and Integrative NeuroscienceT32MH019524 · NIMH · NEW YORK UNIVERSITY · PI KIORPES, LYNNE · 1992 to 2025
$5.2M
Adaptation in decision circuits: temporal history and the efficiency of choiceR01MH104251 · NIMH · NEW YORK UNIVERSITY · PI LOUIE, KENWAY · 2015 to 2019
$1.9M
Neural Mechanisms of Cost and Benefit Integration During Decision-MakingR01DA038063 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GLIMCHER, PAUL W · 2014 to 2018
$1.7M
Neuroeconomic investigation of craving in opioid addictionF32DA039648 · NIDA · NEW YORK UNIVERSITY · PI KONOVA, ANNA BORISOVA · 2015 to 2017
$164k
NEI NIH HHS P30 EY013079NIDA NIH HHS F32 DA039648NIDA NIH HHS R01 DA038063NIMH NIH HHS R01 MH104251NIMH NIH HHS T32 MH019524
6 · The paper itself

Abstract

Craving is thought to be a specific desire state that biases choice toward the desired object, be it chocolate or drugs. A vast majority of people report having experienced craving of some kind. In its pathological form craving contributes to health outcomes in addiction and obesity. Yet despite its ubiquity and clinical relevance we still lack a basic neurocomputational understanding of craving. Here, using an instantaneous measure of subjective valuation and selective cue exposure, we identify a behavioral signature of a food craving-like state and advance a computational framework for understanding how this state might transform valuation to bias choice. We find desire induced by exposure to a specific high-calorie, high-fat/sugar snack good is expressed in subjects' momentary willingness to pay for this good. This effect is selective but not exclusive to the exposed good; rather, we find it generalizes to nonexposed goods in proportion to their subjective attribute similarity to the exposed ones. A second manipulation of reward size (number of snack units available for purchase) further suggested that a multiplicative gain mechanism supports the transformation of valuation during laboratory craving. These findings help explain how real-world food craving can result in behaviors inconsistent with preferences expressed in the absence of craving and open a path for the computational modeling of craving-like phenomena using a simple and repeatable experimental tool for assessing subjective states in economic terms.

Indexed as

Costs and Cost AnalysisCravingModels, PsychologicalAdolescentAdultAlgorithmsBeveragesCandyChoice BehaviorCuesFastingFeeding BehaviorFemaleFood PreferencesHumansMaleattribute similaritycravingeconomic valuemultiplicative gain

Identifiers

PMID29610355
PMCPMC5910816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.