Evidence map›Paper›PMID 29610343›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart.

Héctor Sánchez-Iranzo, María Galardi-Castilla, Andrés Sanz-Morejón, Juan Manuel González-Rosa, Ricardo Costa, Alexander Ernst, Julio Sainz de Aja, Xavier Langa, Nadia Mercader

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 2 syntheses or guidelines pooled it, 182 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Extracellular stiffness regulates cell fate determination and drives the emergence of evolutionary novelty in the teleost heart.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  16. Article
  17. Extracellular matrix remodeling supportsbioRxiv : the preprint server for biology · 2025
    Article
  18. Article
  19. Article
  20. Review

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Héctor Sánchez-IranzoDevelopment of the Epicardium and Its Role During Regeneration Group, Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
María Galardi-CastillaDevelopment of the Epicardium and Its Role During Regeneration Group, Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
Andrés Sanz-MorejónDevelopment of the Epicardium and Its Role During Regeneration Group, Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
Juan Manuel González-RosaDevelopment of the Epicardium and Its Role During Regeneration Group, Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
Ricardo CostaDevelopment of the Epicardium and Its Role During Regeneration Group, Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
Alexander ErnstInstitute of Anatomy, University of Bern, 3000 Bern 9, Switzerland.
Julio Sainz de AjaFunctional Genomics Group, Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
Xavier LangaInstitute of Anatomy, University of Bern, 3000 Bern 9, Switzerland.
Nadia MercaderDevelopment of the Epicardium and Its Role During Regeneration Group, Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain; nadia.mercader@ana.unibe.ch.ORCID 0000-0002-0905-6399
Spanish National Centre for Cardiovascular Research · ESUniversity of Bern · CHUniversitat Autònoma de Barcelona · ES

Funding

European Research Council 337703
6 · The paper itself

Abstract

In the zebrafish (

Indexed as

AnimalsAnimals, Genetically ModifiedBase SequenceCell Adhesion MoleculesCell LineageCold TemperatureCollagen Type XIIEndocardiumExtracellular MatrixFibroblastsFibrosisGene Expression RegulationGenes, ReporterHeartHeart InjuriesMyocardiumCell Adhesion MoleculesCollagen Type XIIpostnb protein, zebrafishRNA, MessengerZebrafish Proteinscardiomyocyte proliferationfibroblast inactivationfibrosisheart regenerationzebrafish

Identifiers

PMID29610343
PMCPMC5910827
OpenAlexW2795900237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.