Evidence map›Paper›PMID 29610335›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Negative regulator of E2F transcription factors links cell cycle checkpoint and DNA damage repair.

Lili Wang, Hanchen Chen, Chongyang Wang, Zhenjie Hu, Shunping Yan

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 58 citations in OpenAlex.

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  8. The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  12. Review
  13. The transcription factor FcMYB3 responds toFrontiers in plant science · 2024
    Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lili WangCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Hanchen ChenCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Chongyang WangCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Zhenjie HuCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Shunping YanCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China spyan@mail.hzau.edu.cn.ORCID 0000-0002-3665-1310
Huazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA damage poses a serious threat to genome integrity and greatly affects growth and development. To maintain genome stability, all organisms have evolved elaborate DNA damage response mechanisms including activation of cell cycle checkpoints and DNA repair. Here, we show that the DNA repair protein SNI1, a subunit of the evolutionally conserved SMC5/6 complex, directly links these two processes in

Indexed as

Gene Expression Regulation, PlantArabidopsisArabidopsis ProteinsCell Cycle CheckpointsDNA DamageDNA RepairE2F Transcription FactorsNuclear ProteinsPlant RootsProtein DomainsArabidopsis ProteinsE2F Transcription FactorsNuclear ProteinsSNI1 protein, Arabidopsiscell cycle checkpointDNA damage repairE2FNSE6SNI1

Identifiers

PMID29610335
PMCPMC5910849
OpenAlexW2795465941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.