Evidence map›Paper›PMID 29610331›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Evolutionary emergence of the

Joaquín Letelier, Javier Terriente, Ivan Belzunce, Adria Voltes, Cristian Alberto Undurraga, Rocio Polvillo, Lucie Devos, Juan J Tena, Ignacio Maeso, Sylvie Retaux and 3 more

Open access · bronzeAbstract readComparative StudyVideo-Audio Media
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

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  7. Segmentation and patterning of the vertebrate hindbrain.Development (Cambridge, England) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Joaquín LetelierCentro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas/Universidad Pablo Olavide, 41013 Sevilla, Spain.
Javier TerrienteDepartment of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain.
Ivan BelzunceDepartment of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain.
Adria VoltesDepartment of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain.
Cristian Alberto UndurragaCentro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas/Universidad Pablo Olavide, 41013 Sevilla, Spain.
Rocio PolvilloCentro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas/Universidad Pablo Olavide, 41013 Sevilla, Spain.
Lucie DevosInstitut des Neurosciences Paris-Saclay, Université Paris-Saclay, Université Paris-Sud, CNRS, 91198 Gif-sur-Yvette, France.
Juan J TenaCentro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas/Universidad Pablo Olavide, 41013 Sevilla, Spain.
Ignacio MaesoCentro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas/Universidad Pablo Olavide, 41013 Sevilla, Spain.
Sylvie RetauxInstitut des Neurosciences Paris-Saclay, Université Paris-Saclay, Université Paris-Sud, CNRS, 91198 Gif-sur-Yvette, France.
José Luis Gomez-SkarmetaCentro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas/Universidad Pablo Olavide, 41013 Sevilla, Spain.
Juan R Martínez-MoralesCentro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas/Universidad Pablo Olavide, 41013 Sevilla, Spain; jrmarmor@upo.es cristina.pujades@upf.edu.ORCID 0000-0002-4650-4293
Cristina PujadesDepartment of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain; jrmarmor@upo.es cristina.pujades@upf.edu.ORCID 0000-0001-6423-7451
Consejo Superior de Investigaciones Científicas · ESUniversitat Pompeu Fabra · ESUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developmental programs often rely on parallel morphogenetic mechanisms that guarantee precise tissue architecture. While redundancy constitutes an obvious selective advantage, little is known on how novel morphogenetic mechanisms emerge during evolution. In zebrafish, rhombomeric boundaries behave as an elastic barrier, preventing cell intermingling between adjacent compartments. Here, we identify the fundamental role of the small-GTPase Rac3b in actomyosin cable assembly at hindbrain boundaries. We show that the novel

Indexed as

Gene Expression Regulation, DevelopmentalActomyosinAnimalsBody PatterningCell MovementCharacidaeChromatinCRISPR-Cas SystemsEvolution, MolecularFishesMorphogenesisMutagenesis, Site-DirectedNeurogenesisPhylogenyrac GTP-Binding ProteinsRhombencephalonActomyosinChromatinrac3b protein, zebrafishrac GTP-Binding Proteinsrfng protein, zebrafishSarcoglycanssgca protein, zebrafishZebrafish Proteinscis-regulatory elementshindbrain boundariesregulatory landscaperhombomeressegmentation

Identifiers

PMID29610331
PMCPMC5910847
OpenAlexW2795997870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.