Evidence map›Paper›PMID 29610299›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Second-order spinal cord pathway contributes to cortical responses after long recoveries from dorsal column injury in squirrel monkeys.

Chia-Chi Liao, Jamie L Reed, Hui-Xin Qi, Eva K Sawyer, Jon H Kaas

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Regressive changes in sizes of somatosensory cuneate nucleus after sensory loss in primates.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Article
  6. Sensory computations in the cuneate nucleus of macaques.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Cortical Reorganization of Sensorimotor Systems and the Role of Intracortical Circuits After Spinal Cord Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chia-Chi LiaoDepartment of Psychology, Vanderbilt University, Nashville, TN 37240.
Jamie L ReedDepartment of Psychology, Vanderbilt University, Nashville, TN 37240.
Hui-Xin QiDepartment of Psychology, Vanderbilt University, Nashville, TN 37240.
Eva K SawyerDepartment of Psychology, Vanderbilt University, Nashville, TN 37240.
Jon H KaasDepartment of Psychology, Vanderbilt University, Nashville, TN 37240 jon.h.kaas@vanderbilt.edu.
Vanderbilt University · US

Funding

Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MIRNICS, KAROLY · 2015 to 2019
$7.1M
FUNCTIONAL ORGANIZATION OF THE SOMATOSENSORY SYSTEMR01NS016446 · NINDS · VANDERBILT UNIVERSITY · PI KAAS, JON H · 1985 to 2018
$6.9M
Cortical reorganization and behavioral recovery after sensory lossR01NS067017 · NINDS · VANDERBILT UNIVERSITY · PI QI, HUI-XIN · 2010 to 2013
$1.3M
NICHD NIH HHS U54 HD083211NINDS NIH HHS R01 NS016446NINDS NIH HHS R01 NS067017
6 · The paper itself

Abstract

Months after the occurrence of spinal cord dorsal column lesions (DCLs) at the cervical level, neural responses in the hand representation of somatosensory area 3b hand cortex recover, along with hand use. To examine whether the second-order spinal cord pathway contributes to this functional recovery, we injected cholera toxin subunit B (CTB) into the hand representation in the cuneate nucleus (Cu) to label the spinal cord neurons, and related results to cortical reactivation in four squirrel monkeys (

Indexed as

Afferent PathwaysAnimalsAxonal TransportAxonsCholera ToxinConvalescenceHandHypesthesiaMedulla OblongataNeuronal PlasticityPosterior Horn CellsRecovery of FunctionSaimiriSomatosensory CortexSpinal Cord InjuriesThalamusCholera Toxinprimatesomatosensory cortexspinal cord injurytactile

Identifiers

PMID29610299
PMCPMC5910841
OpenAlexW2796067778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.