Evidence map›Paper›PMID 29610281›Full record

ArticleMolecular cancer therapeutics2018

Adaptive Resistance to Chemotherapy, A Multi-FAK-torial Linkage.

Kristin N Taylor, David D Schlaepfer

Open access · bronzeAbstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cancer therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
  5. Hippo pathway in intestinal diseases: focusing on ferroptosis.Frontiers in cell and developmental biology · 2023
    Review
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kristin N TaylorDepartment of Reproductive Medicine, University of California, San Diego, School of Medicine, Moores Cancer Center, La Jolla, California.
David D SchlaepferDepartment of Reproductive Medicine, University of California, San Diego, School of Medicine, Moores Cancer Center, La Jolla, California. dschlaepfer@ucsd.edu.
University of California San Diego · US

Funding

Role of Focal Adhesion Kinase In TumorigenesisR01CA102310 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHLAEPFER, DAVID D · 2003 to 2019
$5.0M
Signaling Connections Controlling Cell Motility and InvasionR01CA180769 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHLAEPFER, DAVID D · 2013 to 2017
$1.9M
NCI NIH HHS R01 CA102310NCI NIH HHS R01 CA180769
6 · The paper itself

Abstract

Oncogenes provide tumor cells with a growth and survival advantage. Directed therapies targeted to oncogenic mutations (such as

Indexed as

Focal Adhesion Protein-Tyrosine KinasesAnimalsbeta CateninCell Line, TumorColorectal NeoplasmsMelanomaMiceMutationProto-Oncogene Proteins B-rafXenograft Model Antitumor Assaysbeta CateninFocal Adhesion Protein-Tyrosine KinasesProto-Oncogene Proteins B-raf

Identifiers

PMID29610281
PMCPMC6538033
OpenAlexW2796307849

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.