Evidence map›Paper›PMID 29610256›Full record

ArticleInfection and immunity2018

Myeloid Differentiation Factor 88 and Interleukin-1R1 Signaling Contribute to Resistance to Coccidioides immitis.

Suganya Viriyakosol, Lorraine Walls, Sharon Okamoto, Eyal Raz, David L Williams, Joshua Fierer

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. The Host Response to Coccidioidomycosis.Journal of fungi (Basel, Switzerland) · 2024
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Monocytes and the Host Response to Fungal Pathogens.Frontiers in cellular and infection microbiology · 2020
    Review
  10. Review
  11. The Rise ofFrontiers in immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Suganya ViriyakosolDepartment of Medicine, UC San Diego School of Medicine, San Diego, California, USA.
Lorraine WallsVA Healthcare, San Diego, California, USA.
Sharon OkamotoDepartment of Medicine, UC San Diego School of Medicine, San Diego, California, USA.
Eyal RazDepartment of Medicine, UC San Diego School of Medicine, San Diego, California, USA.
David L WilliamsDepartment of Surgery, James H. Quillen College of Medicine and Center of Excellence in Inflammation, Infectious Disease and Immunity, East Tennessee State University, Johnson City, Tennessee, USA.
Joshua FiererDepartment of Medicine, UC San Diego School of Medicine, San Diego, California, USA jfierer@ucsd.edu.
University of California, San Diego · USVA San Diego Healthcare System · USEast Tennessee State University · US

Funding

Training Innate Immunity: A new approach to the treatment of SepsisR01GM119197 · NIGMS · EAST TENNESSEE STATE UNIVERSITY · PI SHERWOOD, EDWARD R, WILLIAMS, DAVID L. · 2016 to 2024
$4.6M
Innate Immunity and Cardiovascular Function in SepsisR01GM083016 · NIGMS · EAST TENNESSEE STATE UNIVERSITY · PI LI, CHUANFU, WILLIAMS, DAVID L. · 2009 to 2021
$3.8M
AMELIORATION OF SEPSIS BY MACROPHAGE ACTIVATIONR01GM053522 · NIGMS · EAST TENNESSEE STATE UNIVERSITY · PI WILLIAMS, DAVID L. · 1996 to 2015
$3.4M
Control of mucosal immunity by Gas- vs Gai-linked GPCR signaling in dendritic cellsU01AI125860 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAZ, EYAL · 2016 to 2020
$2.3M
NIAID NIH HHS U01 AI125860NIGMS NIH HHS R01 GM053522NIGMS NIH HHS R01 GM083016NIGMS NIH HHS R01 GM119197
6 · The paper itself

Abstract

Rodents are a natural host for the dimorphic pathogenic fungi

Indexed as

AnimalsCoccidioidesCoccidioidomycosisDectin-1Dendritic CellsLectins, C-TypeMacrophages, PeritonealMiceMice, KnockoutMyeloid Differentiation Factor 88Receptors, Interleukin-1 Type IToll-Like Receptor 2Toll-Like Receptor 4Dectin-1IL1R1 protein, mouseLectins, C-TypeMyd88 protein, mouseMyeloid Differentiation Factor 88Receptors, Interleukin-1 Type ITlr2 protein, mouseTlr4 protein, mouseToll-Like Receptor 2Toll-Like Receptor 4CoccidioidesIL-18IL-1R1IL-1Rainnate immunityMyD88TLR2TLR4β-glucan

Identifiers

PMID29610256
PMCPMC5964525
OpenAlexW2796436750

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.