Evidence map›Paper›PMID 29610255›Full record

ArticleInfection and immunity2018

PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani.

Samar Habib, Abdeljabar El Andaloussi, Khaled Elmasry, Aya Handoussa, Manar Azab, Aliaa Elsawey, Ayman Al-Hendy, Nahed Ismail

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Mitochondrial Metabolism in T-Cell Exhaustion.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Characteristics of splenic PD-1Immunologic research · 2024
    Article
  9. Article
  10. Immune response to viscerotropicFrontiers in immunology · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Revisiting the Principles of Designing a Vaccine.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Samar HabibDepartment of Obstetrics and Gynecology, Medical College of Georgia (MCG), Augusta University, Augusta, Georgia, USA.
Abdeljabar El AndaloussiDepartment of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois, USA.
Khaled ElmasryDepartment of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
Aya HandoussaDepartment of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Manar AzabDepartment of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Aliaa ElsaweyDepartment of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Ayman Al-HendyDepartment of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois, USA.
Nahed IsmailDepartment of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA ismail7@uic.edu.
Mansoura University · EGUniversity of Illinois Chicago · USAugusta University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leishmania donovaniAnimalsAntibodiesCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesFemaleImmunotherapyLeishmaniasis, VisceralMiceMice, Inbred BALB CAntibodiesautophagyimmunityimmunotherapyLeishmania donovaniPD1PDL-1T cell exhaustionT cell immunity

Identifiers

PMID29610255
PMCPMC5964517
OpenAlexW2795544179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.