Evidence map›Paper›PMID 29610213›Full record

ArticleJournal of bacteriology2018

Coping with an Essential Poison: a Genetic Suppressor Analysis Corroborates a Key Function of c-di-AMP in Controlling Potassium Ion Homeostasis in Gram-Positive Bacteria.

Fabian M Commichau, Jörg Stülke

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 31 citations in OpenAlex.

  1. ComFB, a widespread family of c-di-NMP receptor proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Biofilm formation byProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. ComFB, a new widespread family of c-di-NMP receptor proteins.bioRxiv : the preprint server for biology · 2024
    Article
  5. Bacterial cell volume regulation and the importance of cyclic di-AMP.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. IPA-3: An Inhibitor of Diadenylate Cyclase ofAntibiotics (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. c-di-AMP Is Essential for the Virulence ofInfection and immunity · 2021
    Article
  13. Review
  14. c-di-AMP-Regulated KInfection and immunity · 2021
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Onward and [KJournal of bacteriology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fabian M CommichauDepartment of General Microbiology, Institute of Microbiology and Genetics, GZMB, Georg-August University Göttingen, Germany.ORCID 0000-0003-0323-7479
Jörg StülkeDepartment of General Microbiology, Institute of Microbiology and Genetics, GZMB, Georg-August University Göttingen, Germany jstuelk@gwdg.de.ORCID 0000-0001-5881-5390
University of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic di-AMP (c-di-AMP) is an important second messenger in bacteria. In most

Indexed as

Cyclic AMPGene Expression Regulation, BacterialGram-Positive BacteriaHomeostasisPhosphoric Diester HydrolasesPhosphorus-Oxygen LyasesPotassiumSecond Messenger SystemsCyclic AMPPhosphoric Diester HydrolasesPhosphorus-Oxygen LyasesPotassiumdiadenylate cyclasephosphodiesterasepotassium uptakesecond messengerStreptococcus pneumoniae

Identifiers

PMID29610213
PMCPMC5971470
OpenAlexW2796382037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.