Evidence map›Paper›PMID 29610198›Full record

ArticleAntimicrobial agents and chemotherapy2018

Pharmacokinetics of Daptomycin in Critically Ill Pediatric Patients.

Charalampos Antachopoulos, Stavroula Ilia, Paschalis Kadiltzoglou, Eirini Baira, Aristides Dokoumetzidis, Evangelos Gikas, Eleni Volakli, Maria Sdougka, George Briassoulis, Emmanuel Roilides

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Charalampos Antachopoulos3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration General Hospital, Thessaloniki, Greece.
Stavroula IliaPediatric Intensive Care Unit, University of Crete, Heraklion, Greece.
Paschalis Kadiltzoglou3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration General Hospital, Thessaloniki, Greece.
Eirini BairaFaculty of Pharmacy, University of Athens, Athens, Greece.
Aristides DokoumetzidisFaculty of Pharmacy, University of Athens, Athens, Greece.
Evangelos GikasFaculty of Pharmacy, University of Athens, Athens, Greece.
Eleni VolakliPediatric Intensive Care Unit, Hippokration General Hospital, Thessaloniki, Greece.
Maria SdougkaPediatric Intensive Care Unit, Hippokration General Hospital, Thessaloniki, Greece.
George BriassoulisPediatric Intensive Care Unit, University of Crete, Heraklion, Greece.
Emmanuel Roilides3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration General Hospital, Thessaloniki, Greece roilides@med.auth.gr.ORCID 0000-0002-0202-364X
Hippocration General Hospital · GRNational and Kapodistrian University of Athens · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmacokinetics of daptomycin (10 mg/kg once daily) was studied in 4 critically ill pediatric patients aged 8 to 14 yrs. The area under the concentration-time curve from time zero to infinity (AUC

Indexed as

AdolescentAnti-Bacterial AgentsBurnsChildCritical IllnessDaptomycinFemaleHumansMaleSepsisAnti-Bacterial AgentsDaptomycinburnchildrencritically illdaptomycinpharmacokineticssepsis

Identifiers

PMID29610198
PMCPMC5971567
OpenAlexW2794625809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.