ArticleAntimicrobial agents and chemotherapy2018
Fungicidal Potency and Mechanisms of θ-Defensins against Multidrug-Resistant Candida Species.
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Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 36 citations in OpenAlex.
- WHO Critical Priority Fungi: A Comprehensive Review of Antifungal Resistance, Emerging Therapeutic Strategies, and the Potential of Antifungal Peptides.International journal of molecular sciences · 2026Review
- Advances in Antimicrobial Peptides: Mechanisms, Design Innovations, and Biomedical Potential.Molecules (Basel, Switzerland) · 2025Review
- The Contribution of Human Antimicrobial Peptides to Fungi.International journal of molecular sciences · 2025Review
- Saliva in Balancing Oral and Systemic Health, Oral Cancer, and Beyond: A Narrative Review.Cancers · 2024Review
- Current Perspectives of Antifungal Therapy: A Special Focus onJournal of fungi (Basel, Switzerland) · 2024Review
- Fangchinoline inhibits growth and biofilm of Candida albicans by inducing ROS overproduction.Journal of cellular and molecular medicine · 2024Article
- Pluronic F-127 Enhances the Antifungal Activity of Fluconazole against ResistantACS infectious diseases · 2024Article
- Small molecules for combating multidrug-resistant superbugActa pharmaceutica Sinica. B · 2022Review
- An Overview of the Potentialities of Antimicrobial Peptides Derived from Natural Sources.Antibiotics (Basel, Switzerland) · 2022Review
- Antifungal Activity, Structural Stability, and Immunomodulatory Effects on Human Immune Cells of Defensin from the LentilMembranes · 2022Article
- A Fun-Guide to Innate Immune Responses to Fungal Infections.Journal of fungi (Basel, Switzerland) · 2022Review
- Article
- Emerging and future strategies in the management of recalcitrant Candida auris.Medical mycology · 2022Review
- Antimicrobial Peptides: An Update on Classifications and Databases.International journal of molecular sciences · 2021Review
- Anti-Inflammatory Effects of RTD-1 in a Murine Model of ChronicAntibiotics (Basel, Switzerland) · 2021Article
- Immunomodulatory Properties of Host Defence Peptides in Skin Wound Healing.Biomolecules · 2021Review
- Promising Drug Candidates and New Strategies for Fighting against the Emerging SuperbugMicroorganisms · 2021Review
- Review
- Host Defense Peptides as Templates for Antifungal Drug Development.Journal of fungi (Basel, Switzerland) · 2020Review
- Novel and potent antimicrobial effects of caspofungin on drug-resistant Candida and bacteria.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Virginia Basso *Department of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Angie Garcia *Department of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Dat Q TranDepartment of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Justin B SchaalDepartment of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID 0000-0002-0069-4917
Patti TranDepartment of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Diana NgoleDepartment of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Younus AqeelDepartment of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Prasad TongaonkarDepartment of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
André J OuelletteDepartment of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Michael E SelstedDepartment of Pathology and Laboratory Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA selsted@med.usc.edu.ORCID 0000-0002-7152-4739
University of Southern California · US
Funding
USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MYLES G COCKBURN · 1985 to 2026
$181.4MSouthern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3MSouthern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0MHost defense-stimulating macrocyclic peptides for treatment of MDR bacterial infectionsR01AI125141 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OUELLETTE, ANDRE J., SELSTED, MICHAEL E · 2016 to 2020
$5.3MMOLECULAR ASPECTS OF LEUKOCYTE ANTIMICROBIAL PEPTIDESR37AI022931 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SELSTED, MICHAEL E · 2000 to 2009
$3.7MRegulation of Mucosal Immunity by Pro- and Anti-inflammatory Salivary DefensinsR01DE021341 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SELSTED, MICHAEL E · 2010 to 2014
$1.9MMOLECULAR ASPECTS OF LEUKOCYTE ANTIMICROBIAL PEPTIDESR01AI022931 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SELSTED, MICHAEL E · 1986 to 2016
$1.7MNCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NCI NIH HHS P30 CA014089NIAID NIH HHS R01 AI022931NIAID NIH HHS R01 AI125141NIAID NIH HHS R37 AI022931NIDCR NIH HHS R01 DE021341
Abstract
Systemic candidiasis is a growing health care concern that is becoming even more challenging due to the growing frequency of infections caused by multidrug-resistant (MDR)
Indexed as
Amphotericin BAnimalsAntifungal AgentsCandidaCandidiasisCaspofunginDefensinsDrug Resistance, Multiple, FungalFluconazoleHistatinsHumansMacaca mulattaMicrobial Sensitivity TestsProtein IsoformsReactive Oxygen SpeciesAmphotericin BAntifungal AgentsCaspofunginDefensinsFluconazoleHistatinsHTN3 protein, humanProtein IsoformsReactive Oxygen Speciestheta-defensinantifungal mechanismsantifungal resistanceantifungalsantifungal therapycandidiasisdefensinsmacrocyclic peptides
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What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.