Evidence map›Paper›PMID 29610140›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Caroline Keegan, Stephan Krutzik, Mirjam Schenk, Philip O Scumpia, Jing Lu, Yan Ling Joy Pang, Brandon S Russell, Kok Seong Lim, Scarlet Shell, Erin Prestwich and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Recognition of Mycobacterium tuberculosis by macrophage Toll-like receptor and its role in autophagy.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Review
  6. Activation of host nucleic acid sensors byCritical reviews in microbiology · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. RNA Sensing ofVaccines · 2020
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Caroline KeeganDivision of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.
Stephan KrutzikDivision of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.
Mirjam SchenkDivision of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.
Philip O ScumpiaDivision of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.
Jing LuDepartment of Molecular, Cell and Developmental Biology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.
Yan Ling Joy PangDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
Brandon S RussellDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0002-7260-6189
Kok Seong LimDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0002-4759-6265
Scarlet ShellDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115.ORCID 0000-0003-1136-1728
Erin PrestwichDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0003-1285-5463
Dan SuDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
David ElashoffDivision of General Internal Medicine, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.
Robert M HershbergCelgene Corporation, Seattle, WA 98102.
Barry R BloomDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115.
John T BelisleDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523; and.ORCID 0000-0002-2539-2798
Sarah FortuneDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115.
Peter C DedonDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0003-0011-3067
Matteo PellegriniDivision of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0001-9355-9564
Robert L ModlinDivision of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095; rmodlin@mednet.ucla.edu.ORCID 0000-0003-4720-031X
University of California, Los Angeles · USMassachusetts Institute of Technology · USHarvard University · USColorado State University · USSingapore-MIT Alliance for Research and Technology · SG

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI YAFFE, MICHAEL B · 1985 to 2020
$25.6M
UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Linda M Liau · 2017 to 2026
$25.2M
Molecular Analysis of the Host Immune Response in LeprosyR01AI022553 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROBERT L MODLIN · 1989 to 2026
$15.7M
TCR GAMMA/DELTA LYMPHOCYTES IN HUMAN SKIN LESIONSR01AR040312 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MODLIN, ROBERT L · 1990 to 2025
$10.4M
Vitamin D Metabolism in LeprosyP50AR063020 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ADAMS, JOHN S · 2012 to 2016
$7.8M
Divergence of Phagocytic and Antimicrobial Programs in LeprosyR01AI047868 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MODLIN, ROBERT L · 2010 to 2014
$2.4M
Anti-TB sterilizing immunity in immune and HIV+ individualsR01HL129887 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 2015 to 2018
$2.1M
Role of Vitamin D Prohormone 25-OHD in the Immune Response to TuberculosisR01HL119068 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LIU, PHILIP T., MODLIN, ROBERT L · 2014 to 2017
$1.5M
NCATS NIH HHS UL1 TR001881NCI NIH HHS P50 CA211015NHLBI NIH HHS R01 HL119068NHLBI NIH HHS R01 HL129887NIAID NIH HHS R01 AI022553NIAID NIH HHS R01 AI047868NIAMS NIH HHS P50 AR063020NIAMS NIH HHS R01 AR040312NIEHS NIH HHS P30 ES002109
6 · The paper itself

Abstract

Upon recognition of a microbial pathogen, the innate and adaptive immune systems are linked to generate a cell-mediated immune response against the foreign invader. The culture filtrate of

Indexed as

Cell DifferentiationGene Regulatory NetworksHumansImmunity, CellularImmunity, InnateInterleukin-12Lymphocyte ActivationMycobacterium tuberculosisReceptors, Pattern RecognitionRNA, BacterialRNA, TransferTh1 CellsTuberculosisInterleukin-12Receptors, Pattern RecognitionRNA, BacterialRNA, Transfer

Identifiers

PMID29610140
PMCPMC5916334
OpenAlexW2795873846

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.