Evidence map›Paper›PMID 29609727›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018

Medical Cannabis and the Treatment of Obstructive Sleep Apnea: An American Academy of Sleep Medicine Position Statement.

Kannan Ramar, Ilene M Rosen, Douglas B Kirsch, Ronald D Chervin, Kelly A Carden, R Nisha Aurora, David A Kristo, Raman K Malhotra, Jennifer L Martin, Eric J Olson and 3 more

Open access · bronzeAbstract readConsensus Statement
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Cannabis and sleep disorders: not ready for prime time? A qualitative scoping review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  5. Article
  6. Review
  7. Cannabis related side effects in otolaryngology: a scoping review.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2021
    Article
  8. Article
  9. Frontiers in pharmacology · 2021
    Article
  10. Article
  11. Effects of Cannabinoids on Sleep and their Therapeutic Potential for Sleep Disorders.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Review
  12. Article
  13. Tetrahydrocannabinol-Rich Extracts FromFrontiers in pharmacology · 2020
    Article
  14. Medical Cannabis, Synthetic Marijuana Extracts, and Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Article
  15. Stop the Attack on Minnesota's Courageous Stance to Allow Its Residents to Sleep Safely.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Article
  16. Medical Cannabis and AASM Position Statement: The Don't Ask, Don't Tell Wishing Well.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Article
  17. Article
  18. Change is the Only Constant in Life (and in Sleep Medicine).Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Review
  19. The Effects of Cannabinoids on Sleep.Journal of primary care & community health
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 1 country.

Kannan RamarDivision of Pulmonary and Critical Care Medicine, Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota.
Ilene M RosenDivision of Sleep Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Douglas B KirschCarolinas Healthcare Medical Group Sleep Services, Charlotte, North Carolina.
Ronald D ChervinUniversity of Michigan Sleep Disorders Center, Ann Arbor, Michigan.
Kelly A CardenSaint Thomas Medical Partners - Sleep Specialists, Nashville, Tennessee.
R Nisha AuroraSchool of Medicine, Johns Hopkins University, Baltimore, Maryland.
David A KristoUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Raman K MalhotraWashington University Sleep Center, St. Louis, Missouri.
Jennifer L MartinVeterans Affairs Greater Los Angeles Healthcare System, North Hills, California.
Eric J OlsonDivision of Pulmonary and Critical Care Medicine, Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota.
Carol L RosenDepartment of Pediatrics, Case Western Reserve University, University Hospitals - Cleveland Medical Center, Cleveland, Ohio.
James A RowleyWayne State University, Detroit, Michigan.
American Academy of Sleep Medicine Board of Directors
Mayo Clinic · USCarolinas Healthcare System · USJohns Hopkins University · USSt. Thomas Medical Group · USUniversity Hospitals of Cleveland · USUniversity of California, Los Angeles · USUniversity of Michigan · USUniversity of Pennsylvania · USUniversity of Pittsburgh · USWashington University in St. Louis · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractThe diagnosis and effective treatment of obstructive sleep apnea (OSA) in adults is an urgent health priority. Positive airway pressure (PAP) therapy remains the most effective treatment for OSA, although other treatment options continue to be explored. Limited evidence citing small pilot or proof of concept studies suggest that the synthetic medical cannabis extract dronabinol may improve respiratory stability and provide benefit to treat OSA. However, side effects such as somnolence related to treatment were reported in most patients, and the long-term effects on other sleep quality measures, tolerability, and safety are still unknown. Dronabinol is not approved by the United States Food and Drug Administration (FDA) for treatment of OSA, and medical cannabis and synthetic extracts other than dronabinol have not been studied in patients with OSA. The composition of cannabinoids within medical cannabis varies significantly and is not regulated. Synthetic medical cannabis may have differential effects, with variable efficacy and side effects in the treatment of OSA. Therefore, it is the position of the American Academy of Sleep Medicine (AASM) that medical cannabis and/or its synthetic extracts should not be used for the treatment of OSA due to unreliable delivery methods and insufficient evidence of effectiveness, tolerability, and safety. OSA should be excluded from the list of chronic medical conditions for state medical cannabis programs, and patients with OSA should discuss their treatment options with a licensed medical provider at an accredited sleep facility. Further research is needed to understand the functionality of medical cannabis extracts before recommending them as a treatment for OSA.

Indexed as

DronabinolHumansMedical MarijuanaOrganizational PolicySleep Apnea, ObstructiveSleep Medicine SpecialtySocieties, MedicalUnited StatesDronabinolMedical Marijuanalong-term effectsmedical cannabisobstructive sleep apneaPAP therapy

Identifiers

PMID29609727
PMCPMC5886446
OpenAlexW2798188107

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.