ReviewMicrobiome2018
Host-microbe interactions in octocoral holobionts - recent advances and perspectives.
Review in Microbiome, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Taxonomy, tissue, and habitat influence mollusk microbial communities.The ISME journal · 2026Pooled it
- Hidden Fungal Diversity of the Precious Mediterranean Red Coral Corallium rubrum.Environmental microbiology reports · 2026Article
- Role of Core Microbiome Shifts in Octocoral Litophyton Under Diurnal Temperature Fluctuations.Microbial ecology · 2026Article
- Spatial and host-specific structuring in symbiont community composition of an endemic Hawaiian octocoral,PeerJ · 2026Article
- Unveiling the Microeukaryotic Landscape of the Red Coral Corallium rubrum Across the Northwestern Mediterranean Sea.Environmental microbiology reports · 2025Article
- Functional stability of Spirochaetota symbionts in the precious octocoral Corallium rubrum under heat stress.Environmental microbiome · 2025Article
- A genomic view of the bacterial family Endozoicomonadaceae in marine symbioses.Communications biology · 2025Review
- Microbiome Composition in a Common Mediterranean Bryozoan Following an Unprecedented Marine Heatwave.Environmental microbiology reports · 2025Article
- Microbiome Dynamics in Early Life Stages of the Precious Mediterranean Red Coral Corallium rubrum.Environmental microbiology reports · 2025Article
- Jellyfish blooms through the microbial lens: temporal changes, cross-species and Jellyfish-water comparisons.Environmental microbiome · 2025Article
- Article
- Florida Keys Cassiopea host benthos-like external microbiomes and a gut dominated by Vibrio, Endozoicomonas and Mycoplasma.PloS one · 2025Article
- Coral garden conservation and restoration: how host taxon andFrontiers in microbiology · 2025Article
- Selective shaping of prokaryotic communities and core symbiont maintenance suggest large-scale aquarium facilities as reservoirs of microbiome diversity in octocorals.Frontiers in microbiology · 2025Article
- Unraveling the impact of marine heatwaves on the Eukaryome of the emblematic Mediterranean red coralISME communications · 2025Article
- An Improved RNA Extraction Method for Octocorals and Its Application in Transcriptome Analysis of Dark-Induced Bleaching Octocoral.Marine biotechnology (New York, N.Y.) · 2024Article
- Genome sequence of the marine alphaproteobacteriumMicrobiology resource announcements · 2024Article
- Insights into the occurrence of phylosymbiosis and co-phylogeny in the holobionts of octocorals from the Mediterranean Sea and Red Sea.Animal microbiome · 2024Article
- Azooxanthellate Palythoa (Cnidaria: Anthozoa) Genomes Reveal Toxin-related Gene Clusters and Loss of Neuronal Genes in Hexacorals.Genome biology and evolution · 2024Article
- Resistance to freezing conditions of endemic Antarctic polychaetes is enhanced by cryoprotective proteins produced by their microbiome.Science advances · 2024Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Octocorals are one of the most ubiquitous benthic organisms in marine ecosystems from the shallow tropics to the Antarctic deep sea, providing habitat for numerous organisms as well as ecosystem services for humans. In contrast to the holobionts of reef-building scleractinian corals, the holobionts of octocorals have received relatively little attention, despite the devastating effects of disease outbreaks on many populations. Recent advances have shown that octocorals possess remarkably stable bacterial communities on geographical and temporal scales as well as under environmental stress. This may be the result of their high capacity to regulate their microbiome through the production of antimicrobial and quorum-sensing interfering compounds. Despite decades of research relating to octocoral-microbe interactions, a synthesis of this expanding field has not been conducted to date. We therefore provide an urgently needed review on our current knowledge about octocoral holobionts. Specifically, we briefly introduce the ecological role of octocorals and the concept of holobiont before providing detailed overviews of (I) the symbiosis between octocorals and the algal symbiont Symbiodinium; (II) the main fungal, viral, and bacterial taxa associated with octocorals; (III) the dominance of the microbial assemblages by a few microbial species, the stability of these associations, and their evolutionary history with the host organism; (IV) octocoral diseases; (V) how octocorals use their immune system to fight pathogens; (VI) microbiome regulation by the octocoral and its associated microbes; and (VII) the discovery of natural products with microbiome regulatory activities. Finally, we present our perspectives on how the field of octocoral research should move forward, and the recognition that these organisms may be suitable model organisms to study coral-microbe symbioses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.