Evidence map›Paper›PMID 29609563›Full record

ArticleBMC pulmonary medicine2018

The association between circulating adiponectin levels, lung function and adiposity in subjects from the general population; data from the Akershus Sleep Apnea Project.

Nina F Caspersen, Helge Røsjø, Allan Flyvbjerg, Mette Bjerre, Anna Randby, Harald Hrubos-Strøm, Torbjørn Omland, Gunnar Einvik

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Body Composition and COPD: A New Perspective.International journal of chronic obstructive pulmonary disease · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Nina F CaspersenDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
Helge RøsjøDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
Allan FlyvbjergSteno Diabetes Center Copenhagen (SDCC), the Capital Region of Denmark and University of Copenhagen, Copenhagen, Denmark.
Mette BjerreMedical Research Laboratory, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Anna RandbyDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
Harald Hrubos-StrømDepartment of Otorhinolaryngology, Division of Surgery, Akershus University Hospital, Lørenskog, Norway.
Torbjørn OmlandDivision of Medicine, Akershus University Hospital, Lørenskog, Norway.
Gunnar EinvikDivision of Medicine, Akershus University Hospital, Lørenskog, Norway. gunnar.einvik@medisin.uio.no.
Akershus University Hospital · NOAarhus University · DKSteno Diabetes Center · DKUniversity of Oslo · NO

Funding

Extrastiftelsen in collaboration with the Norwegian Heart and Lung Association (LHL) 2015/F07781South-Eastern Norway Regional Health Authority 2004219,2007048
6 · The paper itself

Abstract

backgroundCirculating adiponectin (ADPN) levels are inversely associated with disease severity in patients with chronic obstructive pulmonary disease (COPD), while studies assessing the relationship between ADPN and lung function in subjects from the general population have shown diverging results. Accordingly, we hypothesized that ADPN would be associated with lung function in a population-based sample and tested how abdominal adiposity, metabolic syndrome, and systemic inflammation influenced this association.

methodsWe measured total ADPN in serum, forced vital capacity (FVC) and forced expiratory volume during the 1st second (FEV

resultsThe median (interquartile range) level of serum ADPN was 7.6 (5.4-10.4) mg/L. ADPN levels were positively associated with FVC % of predicted (beta 3.4 per SD adiponectin, p < 0.001)) in univariate linear regression analysis, but the association was attenuated in multivariate analysis (standardized beta 0.03, p = 0.573)). Among co-variates only WHR significantly attenuated the relationship. ADPN levels were also associated with FEV

conclusionIn this population-based sample no association between ADPN and lung function was evident after adjustment for covariates related to adiposity.

Indexed as

Pulmonary Disease, Chronic ObstructiveRespiratory Function TestsAbdominal FatAdiponectinAdiposityAdultAge FactorsBody Mass IndexCorrelation of DataFemaleHumansMaleMetabolic SyndromeMiddle AgedNorwayRegistriesAdiponectinAdiponectinAdiposityChronic obstructive pulmonary diseaseLung function

Identifiers

PMID29609563
PMCPMC5879541
OpenAlexW2795731878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.