ArticleAnnals of pediatric endocrinology & metabolism2018
Prevalence of autoimmune thyroiditis in patients with type 1 diabetes: a long-term follow-up study.
Article in Annals of pediatric endocrinology & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Intertwined and unequal causality of type 1 diabetes and autoimmune thyroid disease: Insights from Mendelian randomization.Medicine · 2025Article
- Prevalence and Risk Factors of Autoimmune Thyroid and Coeliac Disease in Type 1 Diabetes Children and Adolescents; A Retrospective Cohort Analysis.Journal of paediatrics and child health · 2025Article
- Prevalence of autoimmune diseases in patients with type 1 diabetes: a scoping review.Einstein (Sao Paulo, Brazil) · 2025Article
- Article
- Beyond the Thyroid: A Narrative Review of Extra-thyroidal Manifestations in Hashimoto's Disease.Cureus · 2024Review
- Type 1 Diabetes and Other Autoimmune Disorders in Children.Pediatric diabetes · 2024Review
- Mapping the path towards novel treatment strategies: a bibliometric analysis of Hashimoto's thyroiditis research from 1990 to 2023.Frontiers in endocrinology · 2023Article
- Predictors of associated and multiple autoimmunity in children and adolescents with type 1 diabetes mellitus.Annals of pediatric endocrinology & metabolism · 2022Article
- The NOD Mouse Beyond Autoimmune Diabetes.Frontiers in immunology · 2022Review
- Graves disease is more prevalent than Hashimoto disease in children and adolescents with type 1 diabetes.Frontiers in endocrinology · 2022Article
- Article
- A pathway level analysis of PFAS exposure and risk of gestational diabetes mellitus.Environmental health : a global access science source · 2021Review
- Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?Open life sciences · 2021Article
- Islet, thyroid and transglutaminase antibodies in adult Bulgarian patients with type 1 diabetes.Endocrine · 2020Article
- Zonulin as a potential putative biomarker of risk for shared type 1 diabetes and celiac disease autoimmunity.Diabetes/metabolism research and reviews · 2020Review
- Causal association between non-thyroidal autoimmune diseases and Graves' ophthalmopathy: A mendelian randomization study.Advances in ophthalmology practice and researchArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeType 1 diabetes mellitus (DM) is associated with autoimmune diseases such as thyroiditis. Therefore, we aimed to investigate the prevalence of autoimmune thyroiditis in patients with type 1 DM.
methodsA total of 102 patients who were diagnosed and followed up (mean age, 8.1±4.0 years) in Ajou University Hospital were enrolled in this study. All the patients were evaluated for beta cell autoimmunity, including insulin autoantibody, glutamic acid decarboxylase antibodies (GADA), and islet cell antibody. Moreover, autoantibodies to thyroid peroxidase and thyroglobulin were assessed at initial diagnosis and annually thereafter.
resultsThe mean patient age (49 men and 53 women) was 19.2±4.8 years. The prevalence of at least one thyroid antibody was 30.4%. Patients with thyroid anti-bodies had a significantly higher frequency of GADA at the time of the diagnosis. Autoimmune thyroiditis was more prevalent in the older age group. GADA was a significant risk factor for development of thyroid autoantibodies after diagnosis of type 1 DM (odds ratio, 4.45; 95% confidence interval, 1.399-14.153).
conclusionsIn patients with type 1 DM, the prevalence of autoimmune thyroiditis was higher than in the general population. Moreover, GADA positivity at diagnosis was associated with thyroid autoimmunity.
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