Evidence map›Paper›PMID 29609421›Full record

ArticleInternational neurourology journal2018

Clinical Efficacy of Solifenacin in the Management of Diabetes Mellitus-Associated Versus Idiopathic Overactive Bladder Symptoms: A Multicenter Prospective Study.

Hoon Choi, Jae Hyun Bae, Cheol Young Oh, Seong Jin Jeong, Woo Jin Ko, Jong Bo Choi, Ju Tae Seo, Dong Hwan Lee, Joon Chul Kim, Kwang Woo Lee and 1 more

Abstract read
In one paragraph

Article in International neurourology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Catheter-Related Bladder Discomfort: How Can We Manage It?International neurourology journal · 2020
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hoon ChoiDepartment of Urology, Korea University Hospital, Korea University College of Medicine, Ansan, Korea.ORCID 0000-0002-8481-8103
Jae Hyun BaeDepartment of Urology, Korea University Hospital, Korea University College of Medicine, Ansan, Korea.ORCID 0000-0001-9862-3545
Cheol Young OhDepartment of Urology, Hallym University College of Medicine, Chuncheon, Korea.
Seong Jin JeongDepartment of Urology, Seoul National University Bundang Hospital, Seongnam, Korea.
Woo Jin KoDepartment of Urology, National Health Insurance Service Ilsan Hospital, Yonsei University College of Medicine, Goyang, Korea.
Jong Bo ChoiDepartment of Urology, Ajou University College of Medicine, Suwon, Korea.
Ju Tae SeoDepartment of Urology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Seoul, Korea.
Dong Hwan LeeDepartment of Urology, Incheon St. Mary's Hospital, The Catholic University College of Medicine, Incheon, Korea.
Joon Chul KimDepartment of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea.
Kwang Woo LeeDepartment of Urology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
Young Ho KimDepartment of Urology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.ORCID 0000-0003-3959-0928

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the clinical efficacy of anticholinergics for managing diabetes mellitus-associated overactive bladder (DM OAB) versus idiopathic overactive bladder (OAB) in Korean women.

methodsWe conducted a multicenter, prospective, parallel-group, open-label, 12-week study. Women (20-65 years old) with OAB symptoms for over 3 months were assigned to the DM OAB and idiopathic OAB groups. Changes in the Overactive Bladder Symptom Score (OABSS), urgency, urinary urgency incontinence, nocturia, daytime frequency according to a voiding diary, uroflowmetry, and postvoid residual urine volume (PVR) at the first visit (V1), week 4 (V2), and week 12 (V3) were compared.

resultsNo significant difference was found between the baseline patient characteristics of the DM OAB and idiopathic OAB groups. Treatment with solifenacin was associated with improvements in urgency, urinary urgency incontinence, nocturia, frequency according to a voiding diary, and the total OABSS between V1 and V2 and between V1 and V3. Moreover, a significant improvement in urgency and urge incontinence was found between V2 and V3 in the DM OAB group. However, no significant changes were found in any other parameters. There were no significant differences between the DM OAB group and the idiopathic OAB group except for urgency and urge incontinence at V2 (3.71 vs. 2.28 and 0.47 vs. 0.32, respectively).

conclusionsThe patients who received solifenacin demonstrated improved urgency, urinary urgency incontinence, nocturia, frequency according to a voiding diary, and total OABSS. Management with solifenacin was equally effective for both DM-related OAB and idiopathic OAB.

Indexed as

AnticholinergicsDiabetes mellitusOveractive urinary bladder

Identifiers

PMID29609421
PMCPMC5885131

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.