Evidence map›Paper›PMID 29608861›Full record

ArticleBiochemistry2018

Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex.

Jiansen Jiang, Flavius L Baiesc, Yasuaki Hiromasa, Xuekui Yu, Wong Hoi Hui, Xinghong Dai, Thomas E Roche, Z Hong Zhou

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

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  18. Crystal structure of the catalytic subunit of bovine pyruvate dehydrogenase phosphatase.Acta crystallographica. Section F, Structural biology communications · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jiansen JiangDepartment of Microbiology, Immunology and Molecular Genetics , University of California, Los Angeles , Los Angeles , California 90095 , United States.ORCID 0000-0002-1692-7906
Flavius L BaiescDepartment of Microbiology, Immunology and Molecular Genetics , University of California, Los Angeles , Los Angeles , California 90095 , United States.
Yasuaki HiromasaFaculty of Agriculture, Attached Promotive Center for International Education and Research of Agriculture , Kyushu University , Fukuoka 812-8581 , Japan.
Xuekui YuDepartment of Microbiology, Immunology and Molecular Genetics , University of California, Los Angeles , Los Angeles , California 90095 , United States.
Wong Hoi HuiCalifornia Nanosystems Institute , University of California, Los Angeles , Los Angeles , California 90095 , United States.
Xinghong DaiDepartment of Microbiology, Immunology and Molecular Genetics , University of California, Los Angeles , Los Angeles , California 90095 , United States.
Thomas E RocheDepartment of Biochemistry and Molecular Biophysics , Kansas State University , Manhattan , Kansas 66506 , United States.
Z Hong ZhouDepartment of Microbiology, Immunology and Molecular Genetics , University of California, Los Angeles , Los Angeles , California 90095 , United States.
California NanoSystems Institute · USKansas State University · USKyushu University · JPUniversity of California, Los Angeles · US

Funding

Genome Structure, Transcription and Packaging of dsRNA VirusesR01AI094386 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Z Hong ZHOU · 2012 to 2026
$6.0M
High-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0M
In situ atomic structures of the Kaposi's sarcoma-associated herpesvirus portal-terminase complex and glycoproteinsR01DE025567 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WU, TING-TING, ZHOU, Z HONG · 2016 to 2024
$4.0M
HIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6M
Direct Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598k
NCRR NIH HHS S10 RR023057NIAID NIH HHS R01 AI094386NIDCR NIH HHS R01 DE025567NIGMS NIH HHS R01 GM071940NIH HHS S10 OD018111
6 · The paper itself

Abstract

Pyruvate dehydrogenase complex (PDC) is a large multienzyme complex that catalyzes the irreversible conversion of pyruvate to acetyl-coenzyme A with reduction of NAD

Indexed as

Amino Acid SequenceBinding SitesCarrier ProteinsCatalysisCatalytic DomainCryoelectron MicroscopyDihydrolipoamide DehydrogenaseDihydrolipoyllysine-Residue AcetyltransferaseHumansProtein ConformationPyruvate Dehydrogenase ComplexPyruvate Dehydrogenase (Lipoamide)Carrier ProteinsDihydrolipoamide DehydrogenaseDihydrolipoyllysine-Residue AcetyltransferasePyruvate Dehydrogenase ComplexPyruvate Dehydrogenase (Lipoamide)

Identifiers

PMID29608861
PMCPMC6033517
OpenAlexW2798224715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.