ArticleThe Journal of organic chemistry2018
Rhodium-Catalyzed [4 + 1] Cyclization via C-H Activation for the Synthesis of Divergent Heterocycles Bearing a Quaternary Carbon.
Article in The Journal of organic chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Article
- Use of pyridazinediones for tuneable and reversible covalent cysteine modification applied to peptides, proteins and hydrogels.Chemical science · 2023Article
- KMolecules (Basel, Switzerland) · 2023Article
- Autoxidation of 4-Hydrazinylquinolin-2(1Molecules (Basel, Switzerland) · 2022Article
- Pd-catalyzed [3 + 2] cycloaddition of cyclic ketimines and trimethylenemethanes towardRSC advances · 2021Article
- Mechanistic Insights into the Dual Directing Group-Mediated C-H Functionalization/AnnulationACS omega · 2021Article
- A Zinc-Mediated Deprotective Annulation Approach to New Polycyclic Heterocycles.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The development of an efficient approach to construct fused polycyclic systems bearing a quaternary carbon center represents a great challenge to synthetic chemistry. Herein, we report a Rh(III)-catalyzed [4 + 1] annulation of propargyl alcohols with various heterocyclic scaffolds under an air atmosphere. Diverse fused heterocycles containing a quaternary carbon center were obtained in moderate to good yields. Additionally, this method features a high atom-economy, metal oxidant free, simple operation, and compatibility with various functional groups.
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Registered trials
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