Evidence map›Paper›PMID 29608795›Full record

ArticleJournal of the American Geriatrics Society2018

Gait Speed and Mobility Disability: Revisiting Meaningful Levels in Diverse Clinical Populations.

Michael E Miller, Jay Magaziner, Anthony P Marsh, Roger A Fielding, Thomas M Gill, Abby C King, Stephen Kritchevsky, Todd Manini, Mary M McDermott, Rebecca Neiberg and 6 more

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
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  9. Longitudinal Associations Between Higher Self-Reported Energy, Gait Speed, and Cognition in Older Adults With Fatigue.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
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  15. Article
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  18. Sex Differences in Recovery Across Multiple Domains Among Older Adults With Hip Fracture.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michael E MillerDepartment of Biostatistical Sciences, School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
Jay MagazinerDepartment of Epidemiology and Public Health, School of Medicine, University of Maryland, Baltimore, Maryland.
Anthony P MarshDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
Roger A FieldingNutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts.
Thomas M GillDepartment of Internal Medicine, Division of Geriatric Medicine, School of Medicine, Yale University, New Haven, Connecticut.ORCID 0000-0002-6450-0368
Abby C KingSchool of Medicine, Stanford University, Stanford, California.
Stephen KritchevskySection on Gerontology and Geriatric Medicine, Department of Internal Medicine, Sticht Center for Healthy Aging and Alzheimer's Prevention, School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
Todd ManiniDepartment of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, Florida.
Mary M McDermottDepartment of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Rebecca NeibergDepartment of Biostatistical Sciences, School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
Denise OrwigDepartment of Epidemiology and Public Health, School of Medicine, University of Maryland, Baltimore, Maryland.
Adam J SantanastoCenter for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
Marco PahorDepartment of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, Florida.
Jack GuralnikDepartment of Epidemiology and Public Health, School of Medicine, University of Maryland, Baltimore, Maryland.
W Jack RejeskiDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
LIFE Investigators

Funding

UF FIELD CENTERU01AG022376 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PAHOR, MARCO · 2003 to 2015
$83.3M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Ravi Jasuja · 2008 to 2026
$23.9M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
Stanford Center for Clinical and Translational Education and Research (SCCTER)UL1UL1RR025744 · NCRR · STANFORD UNIVERSITY · PI GREENBERG, HARRY BERNARD · 2008 to 2011
$22.4M
Sequelae of Hip Fracture in Men: An Epidemiologic StudyR37AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 1992 to 2018
$11.3M
Improving Outcome Measurement for Medical Rehabilitaiton Clinical TrialsR24HD065688 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI JETTE, ALAN MAURICE, ZAFONTE, ROSS DENNIS · 2010 to 2014
$3.9M
Cooperative Lifestyle Intervention Programs (CLIP-II)R18HL076441 · NHLBI · WAKE FOREST UNIVERSITY · PI MARSH, ANTHONY P, REJESKI, WALTER JOHN · 2012 to 2016
$3.1M
ACADEMIC LEADERSHIP AWARD IN DISABILITY AND DISABLING DISORDERSK07AG043587 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2013 to 2017
$645k
NCRR NIH HHS UL1 RR025744NHLBI NIH HHS R18 HL076441NIA NIH HHS K07 AG043587NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG021342NIA NIH HHS P30 AG024827NIA NIH HHS P30 AG028740NIA NIH HHS P30 AG028747NIA NIH HHS P30 AG031679NIA NIH HHS R37 AG009901NIA NIH HHS U01 AG022376NICHD NIH HHS R24 HD065688
6 · The paper itself

Abstract

objectivesTo investigate the heterogeneity of clinically meaningful levels of gait speed relative to self-reported mobility disability (SR-MD).

designFive longitudinal studies with older adults in different health states (onset of acute event, presence of chronic condition, sedentary, community living) were used to explore the relationship between gait speed and SR-MD.

settingLifestyle Interventions and Independence for Elders Pilot (LIFE-P), LIFE, Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN), Baltimore Hip Fracture Study (BHS2), Invecchiare in Chianti (InCHIANTI).

participantsIndividuals aged 65 and older (N=3,540): sedentary, community dwelling (LIFE-P/LIFE), with hip fracture (BHS2), random population-based sample (InCHIANTI), high cardiovascular risk (TRAIN). MEASUREMENTS: Usual-pace gait speed across 3 to 4 m and SR-MD, defined as inability to walk approximately 1 block or climb 1 flight of stairs.

resultsThe mean gait speed of participants without SR-MD was greater than 1.0 m/s in InCHIANTI and TRAIN, 0.79 m/s in LIFE-P/LIFE, and 0.46 m/sec in BHS2. Of individuals with SR-MD, mean gait speed was 0.08 m/s slower in LIFE-P/LIFE, 0.19 m/s slower in TRAIN, 0.22 m/s slower in BHS2, and 0.36 m/s slower in InCHIANTI. The optimal gait speed cutpoint for minimizing SR-MD misclassification rates ranged from 0.3 m/s in BHS2 to 1.0 m/s in TRAIN. In longitudinal analyses, development of SR-MD was dependent on initial gait speed and change in gait speed (p<.001).

conclusionThe relationship between absolute levels of gait speed and SR-MD may be context specific, and there may be variations between populations. Across diverse clinical populations, clinical interpretations of how change in usual pace gait speed relates to development of SR-MD depend on where on the gait speed continuum change occurs.

Indexed as

Mobility LimitationPersons with DisabilitiesSelf ReportAgedAged, 80 and overBaltimoreCross-Sectional StudiesFemaleGaitHumansIndependent LivingLongitudinal StudiesMalePilot ProjectsWalkingWalking Speedmobility disabilitystair climbusual-pace 3- to 4-m gait speed

Identifiers

PMID29608795
PMCPMC5992037

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.