ArticleGenome biology and evolution2018
Divergent Evolutionary Trajectories of Two Young, Homomorphic, and Closely Related Sex Chromosome Systems.
Article in Genome biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed.
- Extreme heterochiasmy and high rates of sex-reversed recombination result in large yet homomorphic sex chromosomes in the Emei moustache toad.Genome research · 2025Article
- Rapid Sex Chromosome Turnover in African Clawed Frogs (Xenopus) and the Origins of New Sex Chromosomes.Molecular biology and evolution · 2024Article
- Sex Chromosome Evolution: Hallmarks and Question Marks.Molecular biology and evolution · 2024Review
- Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis.PLoS genetics · 2023Article
- Slower-X: reduced efficiency of selection in the early stages of X chromosome evolution.Evolution letters · 2023Article
- New insights into Xenopus sex chromosome genomics from the Marsabit clawed frog X. borealis.Journal of evolutionary biology · 2022Article
- A dense linkage map for a large repetitive genome: discovery of the sex-determining region in hybridizing fire-bellied toads (Bombina bombina and Bombina variegata).G3 (Bethesda, Md.) · 2021Article
- Analysis of Sex Chromosome Evolution in the Clade Palaeognathae from Phased Genome Assembly.Genome biology and evolution · 2021Article
- Sex chromosomes in meiotic, hemiclonal, clonal and polyploid hybrid vertebrates: along the 'extended speciation continuum'.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Interaction between sex-determining genes from two species: clues fromPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- A 180 Myr-old female-specific genome region in sturgeon reveals the oldest known vertebrate sex determining system with undifferentiated sex chromosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Sex chromosome degeneration, turnover, and sex-biased expression of sex-linked transcripts in African clawed frogs (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
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- A bird-like genome from a frog: Mechanisms of genome size reduction in the ornate burrowing frog,Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Sex Chromosome Evolution: So Many Exceptions to the Rules.Genome biology and evolution · 2020Review
- Sex Differences in the Recombination Landscape.The American naturalist · 2020Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
There exists extraordinary variation among species in the degree and nature of sex chromosome divergence. However, much of our knowledge about sex chromosomes is based on comparisons between deeply diverged species with different ancestral sex chromosomes, making it difficult to establish how fast and why sex chromosomes acquire variable levels of divergence. To address this problem, we studied sex chromosome evolution in two species of African clawed frog (Xenopus), both of whom acquired novel systems for sex determination from a recent common ancestor, and both of whom have female (ZW/ZZ) heterogamy. Derived sex chromosomes of one species, X. laevis, have a small region of suppressed recombination that surrounds the sex determining locus, and have remained this way for millions of years. In the other species, X. borealis, a younger sex chromosome system exists on a different pair of chromosomes, but the region of suppressed recombination surrounding an unidentified sex determining gene is vast, spanning almost half of the sex chromosomes. Differences between these sex chromosome systems are also apparent in the extent of nucleotide divergence between the sex chromosomes carried by females. Our analyses also indicate that in autosomes of both of these species, recombination during oogenesis occurs more frequently and in different genomic locations than during spermatogenesis. These results demonstrate that new sex chromosomes can assume radically different evolutionary trajectories, with far-reaching genomic consequences. They also suggest that in some instances the origin of new triggers for sex determination may be coupled with rapid evolution sex chromosomes, including recombination suppression of large genomic regions.
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