ArticlePloS one2018
Heart rate dynamics during cardio-pulmonary exercise testing are associated with glycemic control in individuals with type 1 diabetes.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Trial
- State-dependent Gaussian kernel-based power spectrum modification for accurate instantaneous heart rate estimation.PloS one · 2019Trial
- Predictors of Exercise Performance in Type 1 Diabetes: The Role of Hypoglycaemia Fear, Glycaemic Control, and Vascular Health: A Retrospective Cross-Sectional Study.Diabetes, obesity & metabolism · 2026Article
- Health-related fitness benefits following concurrent high-intensity interval training and resistance training in patients with type-1 diabetes or type-2 diabetes.Frontiers in physiology · 2024Article
- Ensemble machine learning reveals key features for diabetes duration from electronic health records.PeerJ. Computer science · 2024Article
- Metabolic and physiological responses to graded exercise testing in individuals with type 1 diabetes using insulin pump therapy.Diabetes, obesity & metabolism · 2023Article
- Pattern of the heart rate performance curve in maximal graded treadmill running from 1100 healthy 18-65 Years old men and women: the 4HAIE study.Frontiers in physiology · 2023Article
- Association of HbA1c with VOMetabolites · 2022Review
- The Potential of Current Noninvasive Wearable Technology for the Monitoring of Physiological Signals in the Management of Type 1 Diabetes: Literature Survey.Journal of medical Internet research · 2022Review
- Heart Rate Performance Curve Is Dependent on Age, Sex, and Performance.Frontiers in public health · 2020Article
- Exercise-based cardiac rehabilitation is associated with a normalization of the heart rate performance curve deflection.Scandinavian journal of medicine & science in sports · 2019Observational
- Supplementary Nitric Oxide Donors and Exercise as Potential Means to Improve Vascular Health in People with Type 1 Diabetes: Yes to NO?Nutrients · 2019Review
- Resistance Isn't Futile: The Physiological Basis of the Health Effects of Resistance Exercise in Individuals With Type 1 Diabetes.Frontiers in endocrinology · 2019Review
- Exercise Testing in Individuals With Diabetes, Practical Considerations for Exercise Physiologists.Frontiers in physiology · 2019Review
- Different Heart Rate Patterns During Cardio-Pulmonary Exercise (CPX) Testing in Individuals With Type 1 Diabetes.Frontiers in endocrinology · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study investigated the degree and direction (kHR) of the heart rate to performance curve (HRPC) during cardio-pulmonary exercise (CPX) testing and explored the relationship with diabetes markers, anthropometry and exercise physiological markers in type 1 diabetes (T1DM). MATERIAL AND
methodsSixty-four people with T1DM (13 females; age: 34 ± 8 years; HbA1c: 7.8 ± 1% (62 ± 13 mmol.mol-1) performed a CPX test until maximum exhaustion. kHR was calculated by a second-degree polynomial representation between post-warm up and maximum power output. Adjusted stepwise linear regression analysis was performed to investigate kHR and its associations. Receiver operating characteristic (ROC) curve was performed based on kHR for groups kHR < 0.20 vs. > 0.20 in relation to HbA1c.
resultsWe found significant relationships between kHR and HbA1c (β = -0.70, P < 0.0001), age (β = -0.23, P = 0.03) and duration of diabetes (β = 0.20, P = 0.04). Stepwise linear regression resulted in an overall adjusted R2 of 0.57 (R = 0.79, P < 0.0001). Our data revealed also significant associations between kHR and percentage of heart rate at heart rate turn point from maximum heart rate (β = 0.43, P < 0.0001) and maximum power output relativized to bodyweight (β = 0.44, P = 0.001) (overall adjusted R2 of 0.44 (R = 0.53, P < 0.0001)). ROC curve analysis based on kHR resulted in a HbA1c threshold of 7.9% (62 mmol.mol-1).
conclusionOur data demonstrate atypical HRPC during CPX testing that were mainly related to glycemic control in people with T1DM.
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