ArticlePLoS genetics2018
Natural allelic variation of the AZI1 gene controls root growth under zinc-limiting condition.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Genome-wide association studies meta-analysis uncovers NOJO and SGS3 novel genes involved in Arabidopsis thaliana primary root development and plasticity.Molecular biology reports · 2024Pooled it
- High-permeability cellulose nanocrystals mediate systemic zinc redistribution through nsLTP2-dependent immune potentiation in plants.Plant biotechnology journal · 2025Article
- Species-wide gene editing of a flowering regulator reveals hidden phenotypic variation.PLoS biology · 2025Article
- Cross-species analysis of abiotic stress in hydroponic leafy crops reveals conserved regulatory networks and key divergences.Frontiers in plant science · 2025Article
- Genome-wide association study using specific-locus amplified fragment sequencing identifies new genes influencing nitrogen use efficiency in rice landraces.Frontiers in plant science · 2023Article
- TheFrontiers in plant science · 2023Article
- Analysis of Arabidopsis non-reference accessions reveals high diversity of metabolic gene clusters and discovers new candidate cluster members.Frontiers in plant science · 2023Article
- Combined Approach of GWAS and Phylogenetic Analyses to Identify New Candidate Genes That Participate inPlants (Basel, Switzerland) · 2022Article
- Physiological and Transcriptomic Analysis ofInternational journal of molecular sciences · 2022Article
- An allelic variant in the ACS7 gene promotes primary root growth in watermelon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- The receptor kinase SRF3 coordinates iron-level and flagellin dependent defense and growth responses in plants.Nature communications · 2022Article
- CROWN ROOTLESS1 binds DNA with a relaxed specificity and activates OsROP and OsbHLH044 genes involved in crown root formation in rice.The Plant journal : for cell and molecular biology · 2022Article
- Plant mineral nutrition and disease resistance: A significant linkage for sustainable crop protection.Frontiers in plant science · 2022Review
- Functions and strategies for enhancing zinc availability in plants for sustainable agriculture.Frontiers in plant science · 2022Review
- Genomic characterization of ZIP genes in pigeonpea (Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- ArabidopsisInternational journal of molecular sciences · 2021Article
- Early transcriptome changes induced by the Geminivirus C4 oncoprotein: setting the stage for oncogenesis.BMC genomics · 2021Article
- Cross-Talks Between Macro- and Micronutrient Uptake and Signaling in Plants.Frontiers in plant science · 2021Review
- Rhizosphere microbiome mediates systemic root metabolite exudation by root-to-root signaling.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- AraPheno and the AraGWAS Catalog 2020: a major database update including RNA-Seq and knockout mutation data for Arabidopsis thaliana.Nucleic acids research · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinc is an essential micronutrient for all living organisms and is involved in a plethora of processes including growth and development, and immunity. However, it is unknown if there is a common genetic and molecular basis underlying multiple facets of zinc function. Here we used natural variation in Arabidopsis thaliana to study the role of zinc in regulating growth. We identify allelic variation of the systemic immunity gene AZI1 as a key for determining root growth responses to low zinc conditions. We further demonstrate that this gene is important for modulating primary root length depending on the zinc and defence status. Finally, we show that the interaction of the immunity signal azelaic acid and zinc level to regulate root growth is conserved in rice. This work demonstrates that there is a common genetic and molecular basis for multiple zinc dependent processes and that nutrient cues can determine the balance of growth and immune responses in plants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.