Evidence map›Paper›PMID 29608143›Full record

ArticleThe Journal of clinical investigation2018

Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression.

Heng Lin, Shuang Wei, Elaine M Hurt, Michael D Green, Lili Zhao, Linda Vatan, Wojciech Szeliga, Ronald Herbst, Paul W Harms, Leslie A Fecher and 9 more

Abstract readPublished Erratum
In one paragraph

Article in The Journal of clinical investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Citrullination in tumor immunity and therapy.The Journal of clinical investigation · 2025
    Review
  6. Article
  7. Review
  8. Review
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  10. Article
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  12. Review
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  14. In vivo CRISPR screens identifyProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Review
  16. Article
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  18. Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Heng Lin
Shuang Wei
Elaine M Hurt
Michael D Green
Lili Zhao
Linda Vatan
Wojciech Szeliga
Ronald Herbst
Paul W Harms
Leslie A Fecher
Pankaj Vats
Arul M Chinnaiyan
Christopher D Lao
Theodore S Lawrence
Max Wicha
Junzo Hamanishi
Masaki Mandai
Ilona Kryczek
Weiping Zou

Funding

Immune Impact on Cancer ChemoresistanceR01CA211016 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2017 to 2021
$3.0M
Effector T Cell Trafficking in Ovarian CancerR01CA190176 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZOU, WEIPING · 2015 to 2019
$2.6M
NCI NIH HHS R01 CA190176NCI NIH HHS R01 CA211016
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID29608143
PMCPMC5873851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.