Evidence map›Paper›PMID 29607961›Full record

ArticleInternal medicine (Tokyo, Japan)2018

A Patient with HCV Infection and a Sustained Virological Response to Direct-acting Antiviral Treatment Who Developed Inclusion Body Myositis.

Toru Kuwano, Norio Akuta, Fumitaka Suzuki, Shunichiro Fujiyama, Yusuke Kawamura, Hitomi Sezaki, Tetsuya Hosaka, Satoshi Saitoh, Masahiro Kobayashi, Yoshiyuki Suzuki and 4 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Toru KuwanoDepartment of Hepatology, Toranomon Hospital, Japan.
Norio AkutaDepartment of Hepatology, Toranomon Hospital, Japan.
Fumitaka SuzukiDepartment of Hepatology, Toranomon Hospital, Japan.
Shunichiro FujiyamaDepartment of Hepatology, Toranomon Hospital, Japan.
Yusuke KawamuraDepartment of Hepatology, Toranomon Hospital, Japan.
Hitomi SezakiDepartment of Hepatology, Toranomon Hospital, Japan.
Tetsuya HosakaDepartment of Hepatology, Toranomon Hospital, Japan.
Satoshi SaitohDepartment of Hepatology, Toranomon Hospital, Japan.
Masahiro KobayashiDepartment of Hepatology, Toranomon Hospital, Japan.
Yoshiyuki SuzukiDepartment of Hepatology, Toranomon Hospital, Japan.
Mariko KobayashiLiver Research Laboratory, Toranomon Hospital, Japan.
Yasuji AraseDepartment of Hepatology, Toranomon Hospital, Japan.
Kenji IkedaDepartment of Hepatology, Toranomon Hospital, Japan.
Hiromitsu KumadaDepartment of Hepatology, Toranomon Hospital, Japan.
Toranomon Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 75-year-old woman who was found to have hepatitis C virus (HCV) infection in 1987. Before treatment in 2016, she was found to have mixed cryoglobulinemia (MC). Direct-acting antiviral (DAA) treatment produced a sustained virological response 12 (SVR12). She noticed gradual muscle weakness in 2015 and the gradual development of dysarthria and dysphagia in 2017. We performed a muscle biopsy that showed inclusion body myositis (IBM). To the best of our knowledge, this is first case of a patient with HCV infection, MC, and IBM, in which MC and IBM did not improve after an SVR12 was obtained by DAA treatment.

Indexed as

AgedAnilidesAntiviral AgentsCarbamatesCryoglobulinemiaCyclopropanesFemaleHepatitis C, ChronicHumansLactams, MacrocyclicMacrocyclic CompoundsMyositis, Inclusion BodyProlineRitonavirSulfonamidesSustained Virologic ResponseAnilidesAntiviral AgentsCarbamatesCyclopropanesLactams, MacrocyclicMacrocyclic CompoundsombitasvirparitaprevirProlineRitonavirSulfonamidesValinedirect-acting antiviralhepatitis C virusinclusion body myositismixed cryoglobulinemiasustained virological response

Identifiers

PMID29607961
PMCPMC6172544
OpenAlexW2795061546

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.