Evidence map›Paper›PMID 29607947›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Multimodality Therapy Including Proton Beam Therapy for AFP Producing Esophageal Cancer with Multiple Liver Metastases.

Tatsuya Miyazaki, Makoto Sohda, Makoto Sakai, Yuji Kumakura, Tomonori Yoshida, Kengo Kuriyama, Takehiko Yokobori, Masaya Miyazaki, Junko Hirato, Toshiyuki Okumura and 3 more

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In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Tatsuya MiyazakiDepartment of General Surgical Science, Gunma University Graduate School, Japan.
Makoto SohdaDepartment of General Surgical Science, Gunma University Graduate School, Japan.
Makoto SakaiDepartment of General Surgical Science, Gunma University Graduate School, Japan.
Yuji KumakuraDepartment of General Surgical Science, Gunma University Graduate School, Japan.
Tomonori YoshidaDepartment of General Surgical Science, Gunma University Graduate School, Japan.
Kengo KuriyamaDepartment of General Surgical Science, Gunma University Graduate School, Japan.
Takehiko YokoboriDepartment of Molecular Pharmacology and Oncology, Gunma University Graduate School, Japan.
Masaya MiyazakiDepartment of Diagnostic and Interventional Radiology, Gunma University Graduate School, Japan.
Junko HiratoDepartment of Pathology, Gunma University Graduate School, Japan.
Toshiyuki OkumuraDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Japan.
Hitoshi IshikawaDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Japan.
Hideyuki SakuraiDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Japan.
Hiroyuki KuwanoDepartment of General Surgical Science, Gunma University Graduate School, Japan.
Gunma University · JPUniversity of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 50-year-old man who presented with a fever and epigastralgia was diagnosed to have esophageal carcinoma which was identified as poorly differentiated adenocarcinoma producing alpha-fetoprotein (AFP) with Barrett's esophagus. Computed tomography revealed multiple liver metastases and lymph node metastases surrounding the stomach. We first performed chemotherapy for the systemic lesions and proton beam therapy for the local control of lesions without complete remission and we were able to successfully control the frequently recurring lesions by proton beam therapy, cryotherapy and chemotherapy. A complete response has been maintained for 16 months and the overall survival time is 4 years and 2 months. Proton beam therapy for primary esophageal cancer and metastatic lesions was thus found to be an effective therapeutic option for such cases.

Indexed as

Proton TherapyAdenocarcinomaalpha-FetoproteinsCombined Modality TherapyEsophageal NeoplasmsHumansLiver NeoplasmsLymphatic MetastasisMaleMiddle AgedTomography, X-Ray Computedalpha-Fetoproteinsalpha-fetoproteinBarrett's cancerproton beam therapy

Identifiers

PMID29607947
PMCPMC6148179
OpenAlexW2795143692

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.