ArticlePublic health nutrition2018
Intakes of magnesium, calcium and risk of fatty liver disease and prediabetes.
Article in Public health nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.Clinical nutrition (Edinburgh, Scotland) · 2022Trial
- Article
- Antioxidant-rich and fibre-enhanced diets reduce liver fibrosis risk in metabolic dysfunction-associated steatotic liver disease: latent class analysis of a cohort study.The British journal of nutrition · 2026Article
- Metabolic associated steatotic liver disease in Qatar: Analysis of dietary patterns and nutrient intake.World journal of hepatology · 2025Article
- Associations between intake of different types of vegetables and metabolic dysfunction-associated fatty liver disease: a population-based study.BMC public health · 2025Article
- Article
- Increased magnesium intake does not mitigate MAFLD risk associated with magnesium deficiency.Scientific reports · 2024Article
- Association between magnesium depletion score and the risk of metabolic dysfunction associated steatotic liver disease: a cross sectional study.Scientific reports · 2024Article
- Blood Magnesium Level and Risk of Hepatocellular Carcinoma in a Prospective Liver Cirrhosis Cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Supplementation of Micro- and Macronutrients-A Role of Nutritional Status in Non-Alcoholic Fatty Liver Disease.International journal of molecular sciences · 2024Review
- Exploring the link: magnesium intake and hepatic steatosis in Americans.Frontiers in nutrition · 2024Article
- Association Between Blood Calcium, Magnesium, and Non-alcoholic Fatty Liver Disease in Adults: a Cohort-Based Case-Control Study.Biological trace element research · 2023Article
- Magnesium and Liver Metabolism Through the Lifespan.Advances in nutrition (Bethesda, Md.) · 2023Review
- Article
- Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage.Nature communications · 2022Article
- Article
- Prediction of Liver Triglyceride Content in Early Lactation Multiparous Holstein Cows Using Blood Metabolite, Mineral, and Protein Biomarker Concentrations.Animals : an open access journal from MDPI · 2022Article
- Magnesium intake is inversely associated with risk of non-alcoholic fatty liver disease among American adults.European journal of nutrition · 2022Article
- Association of Habitual Dietary Intake with Liver Iron-A Population-Based Imaging Study.Nutrients · 2021Article
- 'Magnesium'-the master cation-as a drug-possibilities and evidences.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021Review
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
Abstract
objectiveObesity and insulin resistance play important roles in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Mg intake is linked to a reduced risk of metabolic syndrome and insulin resistance; people with NAFLD or alcoholic liver disease are at high risk of Mg deficiency. The present study aimed to investigate whether Mg and Ca intakes were associated with risk of fatty liver disease and prediabetes by alcohol drinking status.
designWe analysed the association between Ca or Mg intake and fatty liver disease, prediabetes or both prediabetes and fatty liver disease in cross-sectional analyses.
settingThird National Health and Nutrition Examination Survey (NHANES III) follow-up cohort of US adults. SUBJECTS: Nationally representative sample of US adults in NHANES (n 13 489).
resultsAfter adjusting for potential confounders, Mg intake was associated with approximately 30 % reduced odds of fatty liver disease and prediabetes, comparing the highest intake quartile v. the lowest. Mg intake may only be related to reduced odds of fatty liver disease and prediabetes in those whose Ca intake is less than 1200 mg/d. Mg intake may also only be associated with reduced odds of fatty liver disease among alcohol drinkers.
conclusionsThe study suggests that high intake of Mg may be associated with reduced risks of fatty liver disease and prediabetes. Further large studies, particularly prospective cohort studies, are warranted to confirm the findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.