Evidence map›Paper›PMID 29607658›Full record

Trial reportAIDS care2018

Syndemic effect of mental illness and substance use on viral suppression among recently-incarcerated, HIV-infected individuals in the CARE+ Corrections study.

Hannah Yellin, Curt Beckwith, Ann Kurth, Tao Liu, Breana Castonguay, Rudy Patrick, Claudia Trezza, Lauri Bazerman, Irene Kuo

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hannah Yellina Department of Epidemiology and Biostatistics , George Washington University, Milken Institute School of Public Health , Washington , DC , USA.ORCID 0000-0002-4880-3270
Curt Beckwithb Division of Infectious Diseases , The Miriam Hospital , Providence , RI , USA.
Ann Kurthd Yale University School of Nursing , New Haven , CT , USA.
Tao Liue Department of Biostatistics , Brown University School of Public Health , Providence , RI , USA.
Breana Castonguaya Department of Epidemiology and Biostatistics , George Washington University, Milken Institute School of Public Health , Washington , DC , USA.
Rudy Patricka Department of Epidemiology and Biostatistics , George Washington University, Milken Institute School of Public Health , Washington , DC , USA.
Claudia Trezzaa Department of Epidemiology and Biostatistics , George Washington University, Milken Institute School of Public Health , Washington , DC , USA.
Lauri Bazermanb Division of Infectious Diseases , The Miriam Hospital , Providence , RI , USA.
Irene Kuoa Department of Epidemiology and Biostatistics , George Washington University, Milken Institute School of Public Health , Washington , DC , USA.
Milken Institute · USProvidence College · USBrown University · USYale University · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
CARE Corrections: Technology for Jail HIV/HCV Testing, Linkage, and Care (TLC)R01DA030747 · NIDA · MIRIAM HOSPITAL · PI BECKWITH, CURT G, KUO, IRENE · 2010 to 2014
$4.9M
NIAID NIH HHS P30 AI042853NIAID NIH HHS P30 AI117970NIDA NIH HHS R01 DA030747NIDA NIH HHS T32 DA023356
6 · The paper itself

Abstract

Few studies on HIV-related syndemics of co-occurring and mutually reinforcing psychosocial conditions have assessed clinical outcomes in criminal justice (CJ)-involved populations. Baseline data from the CARE+ Corrections study were used to quantify co-occurring mental illness and substance use and examine syndemic effects on viral suppression among 106 CJ-involved HIV-infected individuals. Ninety-one (86%) reported a mental illness diagnosis, 30 (28%) reported hazardous alcohol use, and 61 (58%) were drug dependent. Eighteen (17%) experienced all three conditions. Drug dependence was clustered with mental illness (prevalence odds ratio [POR] 3.20, 95% CI 1.01-10.14) and hazardous alcohol use (POR 2.61, 95% CI 1.03-6.56). The association between syndemic score, representing the number of conditions reported by each individual, and viral suppression was not statistically significant, although 86% of participants with none of these conditions were virally suppressed, compared to 56% of those with all three (p = 0.56). Mental illness and substance use were concentrated in this sample, indicating a need for integrated care services.

Indexed as

PrisonersSyndemicViral LoadAdultFemaleHIV InfectionsHumansMaleMental DisordersMiddle AgedPrevalenceSubstance-Related DisordersTransgender PersonsYoung AdultCriminal justice systemHIVmental illnesssubstance usesyndemics

Identifiers

PMID29607658
PMCPMC6376872
OpenAlexW2795428379

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.