Evidence map›Paper›PMID 29607650›Full record

ArticleAIDS research and human retroviruses2018

Factors Associated with High-Grade Anal Intraepithelial Lesion in HIV-Positive Men in a Southern U.S. City.

Melanie Frank, Cecile D Lahiri, Minh Ly Nguyen, Cyra Christina Mehta, Marina Mosunjac, Lisa Flowers

Open access · greenAbstract read
In one paragraph

Article in AIDS research and human retroviruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Melanie Frank1 Department of Medicine, Emory University School of Medicine , Atlanta, Georgia .
Cecile D Lahiri2 Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine , Atlanta, Georgia .
Minh Ly Nguyen2 Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine , Atlanta, Georgia .
Cyra Christina Mehta4 Department of Biostatistics and Bioinformatics, Rollins School of Public Health , Atlanta, Georgia .
Marina Mosunjac5 Department of Pathology, Emory University School of Medicine , Atlanta, Georgia .
Lisa Flowers3 Grady Ponce de Leon Center , Atlanta, Georgia .
Emory University · USGeorgia Department of Public Health · US

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalKL2TR000455 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$2.9M
Emory R38 Research Training ProgramR38AI140299 · NIAID · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, ROUPHAEL, NADINE GEORGES · 2018 to 2021
$1.4M
Defining Antiretroviral Pharmacology Within HIV-1 Reservoirs of Males and FemalesK23AI124913 · NIAID · EMORY UNIVERSITY · PI LAHIRI, CECILE DELILLE · 2016 to 2020
$943k
NCATS NIH HHS KL2 TR000455NCATS NIH HHS UL1 TR000454NIAID NIH HHS K23 AI124913NIAID NIH HHS P30 AI050409NIAID NIH HHS R38 AI140299NIA NIH HHS U54 AG062334
6 · The paper itself

Abstract

The incidence of anal cancer is increased in HIV-infected patients compared with the general population. Risk factors associated with the anal cancer precursor, high-grade squamous intraepithelial lesion (HSIL), have not been extensively studied in an urban black population with late-stage HIV disease. We performed a retrospective chart review of HIV-infected men at the Grady Ponce de Leon Center HIV Clinic (Atlanta, GA) referred for high-resolution anoscopy (HRA), a procedure where anal tissue is examined under magnification and abnormal areas are biopsied. Between December 2013 and September 2015, 147 men underwent HRA: 72% were black, and 94% were men who have sex with men. CD4 count closest to time of HRA was a median 325 cells/mm

Indexed as

AdultAnus NeoplasmsBiopsyCitiesCytological TechniquesFemaleHistocytochemistryHIV InfectionsHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsSquamous Intraepithelial Lesions of the CervixUnited Statesanal cancerhigh-grade intraepithelial lesionHIVmen who have sex with men (MSM)

Identifiers

PMID29607650
PMCPMC6025845
OpenAlexW2796261954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.