ArticleJournal of Korean medical science2018
Estimated Prevalence of Adolescents with Nonalcoholic Fatty Liver Disease in Korea.
Article in Journal of Korean medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- KASL clinical practice guidelines: Management of nonalcoholic fatty liver disease.Clinical and molecular hepatology · 2021Guideline
- Hepatic Cysts in Korea: Prevalence, Incidence, and Risk Factors Based on a 5.8-Year Follow-up Health Screening Cohort.Journal of Korean medical science · 2026Article
- Risk of complications in adulthood following childhood metabolic dysfunction-associated steatohepatitis based on Korean national health insurance data.Scientific reports · 2026Article
- Effect of breath control on hepatic shear wave elasticity and dispersion in pediatric patients.Ultrasonography (Seoul, Korea) · 2025Article
- Outbreak of Severe Obesity and Metabolic Complications in Children and Adolescents Using the Korea National School Health Examination (KNSHE) From 2017 to 2021.Journal of Korean medical science · 2025Article
- Association between heavy metal exposure and biomarkers for non-alcoholic fatty liver disease in Korean adolescents.Heliyon · 2024Article
- A significant and persistent rise in the global burden of adolescent NAFLD and NASH estimated by BMI.Frontiers in public health · 2024Article
- Correlation between Transient Elastography (FibroscanPediatric gastroenterology, hepatology & nutrition · 2022Article
- Prevalence trends of non-alcoholic fatty liver disease among young men in Korea: A Korean military population-based cross-sectional study.Clinical and molecular hepatology · 2022Article
- Cause of death and cause-specific mortality for primary liver cancer in South Korea: A nationwide population-based study in hepatitis B virus-endemic area.Clinical and molecular hepatology · 2022Article
- Recent Epidemiology and Risk Factors of Nonalcoholic Fatty Liver Disease.Journal of obesity & metabolic syndrome · 2022Review
- A Multicenter Study of Real-world Practice for Management of Abnormal Liver Function Tests in Children with Acute Infectious Diseases.Journal of Korean medical science · 2021Article
- The association of obstructive sleep apnea with dyslipidemia in Korean children and adolescents: a single-center, cross-sectional study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Trends in measures of handgrip strength from 2014 to 2017 among Korean adolescents using the Korean National Health and Nutrition Examination Survey Data.BMC research notes · 2020Article
- Genetic Permissiveness and Dietary Glycemic Load Interact to Predict Type-II Diabetes in the Nile rat (Nutrients · 2019Article
- Quick assessment with controlled attenuation parameter for hepatic steatosis in children based on MRI-PDFF as the gold standard.BMC pediatrics · 2019Article
- Recent research trends and updates on nonalcoholic fatty liver disease.Clinical and molecular hepatology · 2019Review
- Feasibility and Stability of Liver Biopsy before Treatment for Preclinical Nonalcoholic Fatty Liver Studies.Journal of Korean medical science · 2019Article
- Association between hemoglobin glycation index and cardiometabolic risk factors in Korean pediatric nondiabetic population.Annals of pediatric endocrinology & metabolism · 2018Article
- Normal serum alanine aminotransferase and non-alcoholic fatty liver disease among Korean adolescents: a cross-sectional study using data from KNHANES 2010-2015.BMC pediatrics · 2018Article
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Authors and funding
4 authors.
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Abstract
backgroundNonalcoholic fatty liver disease (NAFLD) has become prevalent worldwide in the last decade. However, the recent prevalence of NAFLD in adolescents has not yet been investigated in Korea.
methodsData were obtained from 1,416 participants aged 10-18 years from the Korea National Health and Nutrition Examination Survey conducted in 2010 and 2015. Systolic blood pressure (SBP), diastolic blood pressure (DBP), height, weight, waist circumference (WC), body mass index (BMI), fasting glucose, total cholesterol, high-density lipoprotein (HDL), aspartate aminotransferase (AST), alanine aminotransferase (ALT) level, waist-to-height ratio (WHtR), and pediatric NAFLD fibrosis index (PNFI) were analyzed.
resultsSBP, weight, WC, BMI, WHtR, and total cholesterol level were significantly higher in 2015 than in 2010. Prevalence of NAFLD (BMI ≥ 85th percentile plus ALT > 30 U/L for boys and ALT > 19 U/L for girls) were 4.7% in 2010 and 5.9% in 2015 (P = 0.360). Using various cutoffs for the ALT level (> 40, > 30, > 25.8 U/L for boys and >22.1 U/L for girls) NAFLD prevalence rates were 3.0%, 4.1%, and 5.5% in 2010; 2.9%, 5.0%, and 7.1% in 2015, respectively (P = 0.899, 0.469, and 0.289). Boys had a higher SBP, DBP, height, weight, WC, BMI, WHtR, fasting glucose, total cholesterol, ALT, and lower HDL level than girls. The probability of liver fibrosis using the PNFI varies between 21.3% and 24.5% among NAFLD participants (P < 0.001).
conclusionThe Korean society needs to quickly control the increasing prevalence of NAFLD in adolescents and reduce its complications.
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