Evidence map›Paper›PMID 29607525›Full record

Trial reportThe International journal of eating disorders2018

Remission of loss of control eating and changes in components of the metabolic syndrome.

Lisa M Shank, Marian Tanofsky-Kraff, Rachel M Radin, Lauren B Shomaker, Denise E Wilfley, Jami F Young, Sheila Brady, Cara H Olsen, James C Reynolds, Jack A Yanovski

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Violence in Healthcare Workers Is Associated with Disordered Eating.International journal of environmental research and public health · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Do stress eating or compulsive eating influence metabolic health in a mindfulness-based weight loss intervention?Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lisa M ShankMedical and Clinical Psychology Department, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland.
Marian Tanofsky-KraffMedical and Clinical Psychology Department, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland.ORCID 0000-0003-3871-2233
Rachel M RadinMedical and Clinical Psychology Department, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland.
Lauren B ShomakerSection on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland.
Denise E WilfleyDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Jami F YoungDepartment of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Penninsylvania.
Sheila BradySection on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland.
Cara H OlsenPreventive Medicine and Biostatistics Department, USUHS, Bethesda, Maryland.
James C ReynoldsRadiology and Imaging Sciences Department, Clinical Center, NIH, Bethesda, Maryland.
Jack A YanovskiSection on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland.

Funding

Physiology, Psychology, and Genetics of ObesityZIAHD000641 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI YANOVSKI, JACK A. · 2009 to 2025
$24.8M
Preventing excessive weight gain in adolescent girls at high-risk for adult obesiR01DK080906 · NIDDK · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI TANOFSKY-KRAFF, MARIAN · 2008 to 2011
$1.4M
Intramural NIH HHS Z99 HD999999Intramural NIH HHS ZIA HD000641NIDDK NIH HHS R01 DK080906
6 · The paper itself

Abstract

objectivePediatric loss of control (LOC) eating prospectively predicts the worsening of metabolic syndrome components. However, it is unknown if remission of LOC eating is associated with improvements in metabolic health. Therefore, we conducted a secondary analysis of a trial that enrolled adolescent girls with LOC eating, examining whether LOC remission (vs. persistence) at end-of-treatment was associated with changes in metabolic syndrome components at 6-month follow-up.

methodOne hundred three adolescent girls (age 14.5 ± 1.7 years; BMI-z 1.5 ± 0.3; 56.3% non-Hispanic White, 24.3% non-Hispanic Black) with elevated weight (75th-97th BMI %ile) and reported LOC eating were assessed for metabolic syndrome components at baseline and again six months following the interventions. The main effects of LOC status at end-of-treatment (persistence vs. remission) on metabolic syndrome components (waist circumference, lipids, glucose, and blood pressure) at 6-month follow-up were examined, adjusting for baseline age, depressive symptoms, LOC frequency, fat mass, and height, as well as race, change in height, change in fat mass, and the baseline value of each respective component.

resultsYouth with LOC remission at end-of-treatment had lower glucose (83.9 ± 6.4 vs. 86.5 ± 5.8 mg/dL; p = .02), higher high-density lipoprotein cholesterol (50.3 ± 11.8 vs. 44.8 ± 11.9 mg/dL; p = .01), and lower triglycerides (84.4 ± 46.2 vs. 96.9 ± 53.7 mg/dL; p = .02) at 6-month follow-up when compared with youth with persistent LOC, despite no baseline differences in these components. No other component significantly differed by LOC eating status (ps > .05). DISCUSSION: Reducing LOC eating in adolescent girls may have a beneficial impact on some components of the metabolic syndrome.

Indexed as

AdolescentFeeding and Eating DisordersFemaleHumansMetabolic Syndromeadolescentsloss of control eatingmetabolic syndromeobesityoverweight

Identifiers

PMID29607525
PMCPMC6002918

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.