Evidence map›Paper›PMID 29607443›Full record

ArticleInternational journal of biopharmaceutical sciences2018

Therapeutic Effect of Blueberry Extracts for Acute Myeloid Leukemia.

Colin M McGill, Timothy J Brown, Yuan-Yin Cheng, Lindsey N Fisher, Sriram S Shanmugavelandy, Sally J Gustafson, Kriya L Dunlap, Mary Ann Lila, Mark Kester, Paul T Toran and 2 more

Open access · greenAbstract read
In one paragraph

Article in International journal of biopharmaceutical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Spontaneous and Induced Animal Models for Cancer Research.Diagnostics (Basel, Switzerland) · 2020
    Review
  5. [Advances in the mouse models of myeloid leukemia].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2019
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Colin M McGillDepartment of Chemistry, University of Alaska-Anchorage, Anchorage, AK 99508 USA.
Timothy J BrownDepartment of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA.
Yuan-Yin ChengDepartment of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA.
Lindsey N FisherDepartment of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA.
Sriram S ShanmugavelandyDepartment of Pharmacology, Penn State College of Medicine, Hershey, PA 17033 USA.
Sally J GustafsonDepartment of Chemistry and Biochemistry, University of Alaska-Fairbanks, Fairbanks, AK 99775 USA.
Kriya L DunlapDepartment of Chemistry and Biochemistry, University of Alaska-Fairbanks, Fairbanks, AK 99775 USA.
Mary Ann LilaPlants for Human Health Institute, North Carolina State University, North Carolina Research Campus, Kannapolis, NC 28081 USA.
Mark KesterDepartment of Pharmacology, Penn State College of Medicine, Hershey, PA 17033 USA.
Paul T ToranDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA.
David F ClaxtonDepartment of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA.
Brian M BarthDepartment of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA.
University of Virginia · US

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
Tissue Repository and Animal Models CoreP01CA171983 · NCI · UNIVERSITY OF VIRGINIA · PI FOX, TODD E · 2013 to 2024
$19.9M
Regulation of Ceramide-Based Therapeutics in Acute Myeloid LeukemiaK22CA190674 · NCI · UNIVERSITY OF NEW HAMPSHIRE · PI BARTH, BRIAN MICHAEL · 2016 to 2018
$485k
NCI NIH HHS K22 CA190674NCI NIH HHS P01 CA171983NIGMS NIH HHS P20 GM103395
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is an aggressive hematological malignancy with high incidence in the aging population. In addition, AML is one of the more common pediatric malignancies. Unfortunately, both of these patient groups are quite sensitive to chemotherapy toxicities. Investigation of blueberries specifically as an anti-AML agent has been limited, despite being a prominent natural product with no reported toxicity. In this study, blueberry extracts are reported for the first time to exert a dietary therapeutic effect in animal models of AML. Furthermore,

Indexed as

acute myeloid leukemiablueberrymouse models

Identifiers

PMID29607443
PMCPMC5875929
OpenAlexW2893203022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.