Evidence map›Paper›PMID 29607324›Full record

Trial reportBioMed research international2018

Mammographic Breast Density and Breast Cancer Molecular Subtypes: The Kenyan-African Aspect.

Asim Jamal Shaikh, Maeve Mullooly, Shahin Sayed, Rose Ndumia, Innocent Abayo, James Orwa, Ronald Wasike, Zahir Moloo, Gretchen L Gierach

Abstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The epidemiologic factors associated with breast density: A review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Asim Jamal ShaikhSection of Medical Oncology, Department of Medicine, The Aga Khan University Hospital, Nairobi, Kenya.ORCID 0000-0002-2043-301X
Maeve MulloolyDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Shahin SayedDepartment of Pathology, The Aga Khan University Hospital, Nairobi, Kenya.
Rose NdumiaDepartment of Radiology, The Aga Khan University Hospital, Nairobi, Kenya.
Innocent AbayoDepartment of Medical Education, The Aga Khan University Hospital, Nairobi, Kenya.
James OrwaDepartment of Statistics and Epidemiology, The Aga Khan University Hospital, Nairobi, Kenya.
Ronald WasikeSection of Breast Surgery, Department of Surgery, The Aga Khan University Hospital, Nairobi, Kenya.
Zahir MolooDepartment of Pathology, The Aga Khan University Hospital, Nairobi, Kenya.
Gretchen L GierachDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionData examining mammographic breast density (MBD) among patients in Sub-Saharan Africa are sparse. We evaluated how MBD relates to breast cancer characteristics in Kenyan women undergoing diagnostic mammography.

methodsThis cross-sectional study included women with pathologically confirmed breast cancers (

resultsMedian PD and dense area were 24.9% and 85.3 cm

conclusionsOur findings show discordant relationships between MBD and molecular tumor subtypes to those previously observed in Western populations. The relatively low breast density observed at diagnosis may have important implications for cancer prevention initiatives in Kenya. Subsequent larger studies are needed to confirm these findings.

Indexed as

Breast DensityAgedAge FactorsCross-Sectional StudiesFemaleHumansKenyaMiddle AgedNeoplasm ProteinsReceptors, EstrogenTriple Negative Breast NeoplasmsNeoplasm ProteinsReceptors, Estrogen

Identifiers

PMID29607324
PMCPMC5828539

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.