Evidence map›Paper›PMID 29607044›Full record

ArticleEcology and evolution2018

Ancient pathogen DNA in human teeth and petrous bones.

Ashot Margaryan, Henrik B Hansen, Simon Rasmussen, Martin Sikora, Vyacheslav Moiseyev, Alexandr Khoklov, Andrey Epimakhov, Levon Yepiskoposyan, Aivar Kriiska, Liivi Varul and 4 more

Open access · goldAbstract read
In one paragraph

Article in Ecology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Quick Analysis of Sedimentary Ancient DNA Using quicksand.Molecular biology and evolution · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. An Adagio for Viruses, Played Out on Ancient DNA.Genome biology and evolution · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 5 countries.

Ashot MargaryanCentre for GeoGenetics Natural History Museum of Denmark University of Copenhagen Copenhagen Denmark.ORCID 0000-0002-2576-2429
Henrik B HansenCentre for GeoGenetics Natural History Museum of Denmark University of Copenhagen Copenhagen Denmark.
Simon RasmussenDepartment of Bio and Health Informatics Technical University of Denmark Kongens Lyngby Denmark.
Martin SikoraCentre for GeoGenetics Natural History Museum of Denmark University of Copenhagen Copenhagen Denmark.
Vyacheslav MoiseyevPeter the Great Museum of Anthropology and Ethnography (Kunstkamera) RASSt Petersburg Russia.
Alexandr KhoklovSamara State University of Social Sciences and Education Samara Russia.
Andrey EpimakhovInstitute of History and Archaeology RAS (South Ural Department) South Ural State University Chelyabinsk Russia.
Levon YepiskoposyanInstitute of Molecular Biology National Academy of Sciences Yerevan Armenia.
Aivar KriiskaSchool of Humanities Tallinn University Tallinn Estonia.
Liivi VarulSchool of Humanities Tallinn University Tallinn Estonia.
Lehti SaagDepartment of Evolutionary Biology Institute of Molecular and Cell Biology University of Tartu Tartu Estonia.
Niels LynnerupDepartment of Forensic Medicine Section of Forensic Pathology University of Copenhagen Copenhagen East Denmark.
Eske WillerslevCentre for GeoGenetics Natural History Museum of Denmark University of Copenhagen Copenhagen Denmark.
Morten E AllentoftCentre for GeoGenetics Natural History Museum of Denmark University of Copenhagen Copenhagen Denmark.
University of Copenhagen · DKTallinn University · EEEstonian Biocentre · EEPeter the Great's Museum of Anthropology and Ethnography · RURussian-Armenian University · AMSamara State University of Social Sciences and Education · RUSouth Ural State University · RUTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent ancient DNA (aDNA) studies of human pathogens have provided invaluable insights into their evolutionary history and prevalence in space and time. Most of these studies were based on DNA extracted from teeth or postcranial bones. In contrast, no pathogen DNA has been reported from the petrous bone which has become the most desired skeletal element in ancient DNA research due to its high endogenous DNA content. To compare the potential for pathogenic aDNA retrieval from teeth and petrous bones, we sampled these elements from five ancient skeletons, previously shown to be carrying

Indexed as

ancient DNAancient pathogensmetagenomicspetrous boneplagueYersinia pestis

Identifiers

PMID29607044
PMCPMC5869295
OpenAlexW2789735122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.