Double-blind, Placebo-controlled Trial to Evaluate the Effectiveness of

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

1. Comparison of the Efficacy of Melasma Treatments: A Network Meta-Analysis of Randomized Controlled Trials.Frontiers in medicine · 2021
   Pooled it
2. Melasma Treatment: An Evidence-Based Review.American journal of clinical dermatology · 2020
   Pooled it
3. Cutaneous Aging in Skin of Color: A Narrative Review.American journal of clinical dermatology · 2026
   Review
4. Visible Light Protection Strategies for Diverse Populations.Dermatology and therapy · 2026
   Review
5. Systematic Review and Meta-Analysis of Treatments on Melasma Area Severity Index and Quality of Life.Pharmaceutics · 2025
   Review
6. Clinical Trials Conducted on Herbal Remedies for the Treatment of Melasma: A Scoping Review.Journal of cosmetic dermatology · 2025
   Article
7. Personalized Photoprotection: Expert Consensus and Recommendations From a Delphi Study Among Dermatologists.Photodermatology, photoimmunology & photomedicine · 2025
   Article
8. An Update on New and Existing Treatments for the Management of Melasma.American journal of clinical dermatology · 2024
   Review
9. Management of Melasma: Laser and Other Therapies-Review Study.Journal of clinical medicine · 2024
   Review
10. The Impact of Antioxidants on Vitiligo and Melasma: A Scoping Review and Meta-Analysis.Antioxidants (Basel, Switzerland) · 2023
    Article
11. Clinical Applications ofLife (Basel, Switzerland) · 2023
    Review
12. Systemic Photoprotection in Melanoma and Non-Melanoma Skin Cancer.Biomolecules · 2023
    Review
13. Review on photoprotection: a clinician's guide to the ingredients, characteristics, adverse effects, and disease-specific benefits of chemical and physical sunscreen compounds.Archives of dermatological research · 2023
    Review
14. Photoprotection in skin of color.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Review
15. Uses ofJournal of clinical medicine · 2023
    Article
16. Update on Melasma-Part II: Treatment.Dermatology and therapy · 2022
    Review
17. Dermatologic Applications ofThe Journal of clinical and aesthetic dermatology · 2021
    Review
18. Iron oxides in novel skin care formulations attenuate blue light for enhanced protection against skin damage.Journal of cosmetic dermatology · 2021
    Article
19. Traditional Asian Herbs in Skin Whitening: The Current Development and Limitations.Frontiers in pharmacology · 2020
    Review
20. New oral and topical approaches for the treatment of melasma.International journal of women's dermatology · 2019
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

6 authors at 1 institution in 2 countries.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as