Evidence map›Paper›PMID 29606581›Full record

ArticleNeuron2018

RIM C

Arthur P H de Jong, Carlos M Roggero, Meng-Ru Ho, Man Yan Wong, Chad A Brautigam, Josep Rizo, Pascal S Kaeser

Open access · greenAbstract read
In one paragraph

Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Molecular definition of distinct active zone protein machineries for CabioRxiv : the preprint server for biology · 2023
    Article
  12. Nanoscale Phosphoinositide Distribution on Cell Membranes of Mouse Cerebellar Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Synaptotagmin rings as high-sensitivity regulators of synaptic vesicle docking and fusion.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Munc13-1 is a CaNeuron · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Arthur P H de JongDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Carlos M RoggeroDepartments of Biophysics, Biochemistry, and Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Meng-Ru HoDepartments of Biophysics, Biochemistry, and Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Man Yan WongDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Chad A BrautigamDepartments of Biophysics and Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Josep RizoDepartments of Biophysics, Biochemistry, and Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Pascal S KaeserDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: kaeser@hms.harvard.edu.
Harvard University · USThe University of Texas Southwestern Medical Center · USInstitute of Biological Chemistry, Academia Sinica · TW

Funding

Mechanisms of neurotransmitter release and its regulationR35NS097333 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2017 to 2024
$7.0M
Dissecting the assembly of vertebrate neurotransmitter release sites-Research Supplements to Promote Diversity in Health-Related ResearchR01MH113349 · NIMH · HARVARD MEDICAL SCHOOL · PI Pascal Simon Kaeser · 2017 to 2026
$6.1M
Molecular Dissection of Active Zone Functions in Neurotransmitter ReleaseR01NS083898 · NINDS · HARVARD MEDICAL SCHOOL · PI Pascal Simon Kaeser · 2014 to 2026
$5.9M
Super-Resolution ImagingP30NS072030 · NINDS · HARVARD MEDICAL SCHOOL · PI REGEHR, WADE G · 2011 to 2020
$5.8M
Acquisition of upgrades for 800 MHz NMR consoleS10OD018027 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2014 to 2014
$376k
600MHz Varian VNMRS Console UpgradeS10RR026461 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI ROSEN, MICHAEL K · 2010 to 2010
$254k
NCRR NIH HHS S10 RR026461NIH HHS S10 OD018027NIMH NIH HHS R01 MH113349NINDS NIH HHS P30 NS072030NINDS NIH HHS R01 NS083898NINDS NIH HHS R35 NS097333
6 · The paper itself

Abstract

Rapid and efficient synaptic vesicle fusion requires a pool of primed vesicles, the nearby tethering of Ca

Indexed as

Amino Acid SequenceAnimalsATP-Binding Cassette TransportersCell MembraneFemaleHEK293 CellsHumansMaleMiceMice, KnockoutPhosphatidylinositol 4,5-DiphosphatePresynaptic TerminalsProtein BindingProtein DomainsSynaptic TransmissionAbca4 protein, mouseATP-Binding Cassette TransportersPhosphatidylinositol 4,5-Diphosphateactive zoneC2 domainneurotransmitter releasePIP(2)RIMsecretionsynaptic vesicle

Identifiers

PMID29606581
PMCPMC5910229
OpenAlexW2794664352

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.