Evidence map›Paper›PMID 29606101›Full record

ArticleBMC cancer2018

Validation of the Taiwan Chinese version of the EORTC QLQ-CR29 to assess quality of life in colorectal cancer patients.

Ming-Hung Shen, Ling-Ping Chen, Thien-Fiew Ho, Ying-Yih Shih, Ching-Shui Huang, Wei-Chu Chie, Chi-Cheng Huang

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07372300 (The Efficacy of Combination of Modulated Electro-Hyperthermia), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07372300 phase3recruitingnot on this mapstarted 2025, after this paper: background citation

The Efficacy of Combination of Modulated Electro-Hyperthermia(mEHT) in The Multimodality Management in Locally Advanced Rectal Cancer: A Multicenter Phase 3 Randomized Control Trial.

TypeinterventionalSponsorShih-Kai HungRan2025 to 2027Enrolled126ConditionsLocally Advanced Rectal CarcinomaArmsHyperthermia
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ming-Hung ShenDivision of Colorectal Surgery, Department of Surgery, Cathay General Hospital, No.280, Jen-I Rd. Sec.4, Daan Dist., Taipei City, 106, Taiwan.
Ling-Ping ChenDivision of Hematology and Oncology, Department of Medicine, Cathay General Hospital, No.280, Jen-I Rd. Sec.4, Daan Dist., Taipei City, 106, Taiwan.
Thien-Fiew HoDepartment of Surgery, Cathay General Hospital Sijhih, No.2, Lane 59, Jian-Cheng Rd., Sijhih Dist., New Taipei City, 221, Taiwan.
Ying-Yih ShihDepartment of Medicine, Cathay General Hospital Sijhih, No.2, Lane 59, Jian-Cheng Rd., Sijhih Dist., New Taipei City, 221, Taiwan.
Ching-Shui HuangDivision of General Surgery, Department of Surgery, Cathay General Hospital, No.280, Jen-I Rd. Sec.4, Daan Dist., Taipei City, 106, Taiwan.
Wei-Chu ChieInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, No.17, Xu-Zhou Rd., Zhongzheng Dist., Taipei City, 100, Taiwan.
Chi-Cheng HuangDivision of General Surgery, Department of Surgery, Fu-Jen Catholic University Hospital, No.69; Gui-Zi Rd., Taishan Dist., New Taipei City, 243, Taiwan. chishenh74@gmail.com.ORCID 0000-0003-4378-4776

Funding

Cathay General Hospital CGH-MR-B10427National Science Council MOST-103-2314-B-281-004-MY2
6 · The paper itself

Abstract

backgroundThe increasing incidence of colorectal cancer in Taiwan has generated a need for a disease-specific quality-of-life measuring instrument. We aimed to validate the Taiwan Chinese version of the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQ-CR29.

methodsA total of 108 patients were interviewed. Convergent and discriminant validity, Cronbach's alpha coefficient, test-retest reliability, and known-groups comparisons were used to examine the reliability and validity.

resultsWe found good internal consistency reliability for multi-item scales of the QLQ-C30 and QLQ-CR29, except for the cognitive function and pain scale of the QLQ-C30. Patients in the active treatment group reported compromised functional scale scores (global health status/quality of life, QLQ-C30) and worse symptoms (blood and mucus in stool, QLQ-CR29) than those in the follow-up group. Similar results were found in comparisons based on Eastern Cooperative Oncology Group (ECOG) Performance Status and Bristol Stool Scale: higher physical function/sexual interest, less fatigue/urine frequency symptoms for patients with the lowest ECOG Performance Status (Grade 0), and borderline worse stool frequency scores from Types 5 and 6 patients on the Bristol Stool Scale.

conclusionThe study validated the Taiwan Chinese version of the EORTC QLQ-C30 and QLQ-CR29. The clinical applicability warrants further studies with greater number of participants.

Indexed as

Quality of LifeAdultAgedAged, 80 and overColorectal NeoplasmsFemaleHumansMaleMiddle AgedPublic Health SurveillanceReproducibility of ResultsSurveys and QuestionnairesTaiwanYoung AdultColorectal cancerEORTC QLQ-C30 and QLQ-CR29Quality of lifeTaiwan ChineseValidation study

Identifiers

PMID29606101
PMCPMC5880067

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.