Evidence map›Paper›PMID 29605094›Full record

ArticleKidney international2018

Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate.

Morgan E Grams, Yingying Sang, Shoshana H Ballew, Juan Jesus Carrero, Ognjenka Djurdjev, Hiddo J L Heerspink, Kevin Ho, Sadayoshi Ito, Angharad Marks, David Naimark and 12 more

Erratum issuedOpen access · greenAbstract readMulticenter Study
In one paragraph

Article in Kidney international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 109 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 4 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 4 syntheses or guidelines pooled it, 195 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Simultaneous initiation of finerenone and empagliflozin across the spectrum of kidney risk in the CONFIDENCE trial.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Trial
  7. Trial
  8. Article
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  13. The kidney failure risk equation in people with CKD and multimorbidity: the effect of competing mortality risks.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Observational
  14. Review
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 16 institutions in 11 countries.

Morgan E GramsDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Yingying SangDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Shoshana H BallewDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Juan Jesus CarreroDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Ognjenka DjurdjevDepartment of Measurement and Reporting, Provincial Health Service Authority, Vancouver, British Columbia, Canada.
Hiddo J L HeerspinkDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, the Netherlands.
Kevin HoDepartment of Nephrology, Geisinger Medical Center, Danville, Pennsylvania, USA.
Sadayoshi ItoDivision of Nephrology, Endocrinology and Hypertension, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Angharad MarksInstitute of Applied Health Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
David NaimarkSunnybrook Hospital, University of Toronto, Toronto, Ontario, Canada.
Danielle M NashInstitute for Clinical Evaluative Sciences, Ontario, Canada.
Sankar D NavaneethanSection of Nephrology, Baylor College of Medicine, Houston, Texas, USA.
Mark SarnakDivision of Nephrology at Tufts Medical Center, Boston, Massachusetts, USA.
Benedicte StengelINSERM UMR1018, CESP Center for Research in Epidemiology and Population Health, Team 5, Villejuif, France, UVSQ and UMRS 1018, Paris-Sud University, Villejuif, France.
Frank L J VisserenDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Angela Yee-Moon WangDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong.
Anna KöttgenDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
Andrew S LeveyDivision of Nephrology at Tufts Medical Center, Boston, Massachusetts, USA.
Mark WoodwardDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; The George Institute for Global Health, University of Oxford, Oxford, UK; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Kai-Uwe EckardtDepartment of Nephrology and Medical Intensive Care, Charité, Universitätsmedizin Berlin, Berlin, Germany.
Brenda HemmelgarnCumming School of Medicine, Division of Nephrology, and Department of Community Health Sciences, University of Calgary, Alberta, Canada.
Josef CoreshDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. Electronic address: ckdpc@jhmi.edu.
Johns Hopkins University · USTufts Medical Center · USBaylor College of Medicine · USCharité - Universitätsmedizin Berlin · DEGeisinger Medical Center · USInstitute for Clinical Evaluative Sciences · CAKarolinska Institutet · SEProvincial Health Services Authority · CAQueen Mary Hospital · CNTohoku University · JPUniversité Paris-Sud · FRUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NLUniversity of Aberdeen · GBUniversity of Calgary · CAUniversity of Toronto · CA

Funding

ZOVIRAX CREAM TO TREAT HERPES LABIALIS IN ADOLESCENTSM01RR000827 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZELL, JASON · 1985 to 2010
$74.3M
QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
Scientific and Data Coordinating Center(SDCC) for the P*U01DK060990 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI FELDMAN, HAROLD I · 2001 to 2017
$50.1M
Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
ZINC AND CA EDTA THERAPY OF PLUMBISMM01RR000052 · NCRR · JOHNS HOPKINS UNIVERSITY · PI NICHOLSON, WANDA K · 1985 to 2007
$37.3M
Study of the Care and Outcomes of REnal InsufficiencyU01DK060902 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI GO, ALAN S · 2001 to 2025
$19.5M
Prospective Renal Insufficiency Cohort Evaluation:PRICEU01DK060984 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI COHEN, DEBBIE L · 2001 to 2025
$17.0M
YQ MICRODELETIONS AND MALE INFERTILITYP20RR011145 · NCRR · CHARLES R. DREW UNIVERSITY OF MED &SCI · PI SINHA-HIKIM, INDRANI · 1995 to 2009
$17.0M
Prospective Cohort Study of Chronic Renal InsufficiencyU01DK061028 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAO, PANDURANGA S · 2001 to 2025
$16.9M
Limited Competition for the Continuation of the Chronic Renal Insufficiency Cohort (CRIC) Hopkins Clinical CenterU01DK061022 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI APPEL, LAWRENCE JOHN · 2001 to 2025
$15.7M
Proposal for a Chicago-CRIC Clinical CenterU01DK060980 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LASH, JAMES P. · 2001 to 2025
$15.4M
WARCEFP20RR011104 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI HIGGINBOTHAM, EVE J. · 1995 to 2009
$14.5M
HSRD VA SDR 02-237NCATS NIH HHS UL1 TR000003NCATS NIH HHS UL1 TR000424NCATS NIH HHS UL1 TR003098NCRR NIH HHS M01 RR000052NCRR NIH HHS M01 RR000827NCRR NIH HHS P20 RR011104NCRR NIH HHS P20 RR011145NHLBI NIH HHS HHSN268200900049CNIDDK NIH HHS K08 DK092287NIDDK NIH HHS K23 DK067303NIDDK NIH HHS K24 DK002818NIDDK NIH HHS R01 DK072231NIDDK NIH HHS R01 DK096920NIDDK NIH HHS R01 DK100446NIDDK NIH HHS R01 DK139225NIDDK NIH HHS U01 DK060902NIDDK NIH HHS U01 DK060963NIDDK NIH HHS U01 DK060980NIDDK NIH HHS U01 DK060984NIDDK NIH HHS U01 DK060990NIDDK NIH HHS U01 DK061022NIDDK NIH HHS U01 DK061028NIGMS NIH HHS P30 GM103337
6 · The paper itself

Abstract

Patients with chronic kidney disease and severely decreased glomerular filtration rate (GFR) are at high risk for kidney failure, cardiovascular disease (CVD) and death. Accurate estimates of risk and timing of these clinical outcomes could guide patient counseling and therapy. Therefore, we developed models using data of 264,296 individuals in 30 countries participating in the international Chronic Kidney Disease Prognosis Consortium with estimated GFR (eGFR)s under 30 ml/min/1.73m

Indexed as

Decision Support TechniquesGlomerular Filtration RateAdultAgedCardiovascular DiseasesDisease ProgressionFemaleHumansKidneyMaleMarkov ChainsMiddle AgedMonte Carlo MethodPrognosisRenal InsufficiencyRenal Insufficiency, Chronicalbuminuriacardiovascular diseasechronic kidney disease

Identifiers

PMID29605094
PMCPMC5967981
OpenAlexW2794560981

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.